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Breast Cancers 8

Selected Risks and Benefits after 5 Years of combined estrogen and progestogen HRT for all women aged 50-79 (WHI Study, 2002) OESTROGEN WITH PROGESTOGEN. 10,000 Women Years. * Not statistically significant. Pulmonary Embolism 8. Breast Cancers 8. CVD* 7. Stroke 8. Increase.

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Breast Cancers 8

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  1. Selected Risks and Benefits after 5 Years of combined estrogen and progestogen HRT for all women aged 50-79 (WHI Study, 2002)OESTROGEN WITH PROGESTOGEN 10,000 Women Years * Not statistically significant Pulmonary Embolism 8 Breast Cancers 8 CVD* 7 Stroke 8 Increase Decrease 8 Bowel and Uterine Cancers 10 Fractures Hip and Spine MacLennan

  2. Selected Risks and Benefits after 7 Years of estrogen only HRT for all women aged 50-79 (WHI Study, 2004)OESTROGEN ONLY 10,000 Women Years * Not statistically significant Stroke 12 Pulmonary embolism* 3 Bowel Cancer* 1 Increase Decrease 5 CVD* 8 Breast Cancers* 12 Fractures Hip and Spine MacLennan

  3. Combined Estrogen + Progestogen HRT outcomes when initiated under age 60.(Data from 5,522 women in WHI Study) 10,000 Women Years ESTROGEN AND PROGESTOGEN CVD 7 Breast Cancer 2 Stroke 4 Pulmonary Embolism 1 Increase Decrease 7 Deaths . . . . 13 Diabetes 59 56 All Fractures MacLennan

  4. Estrogen only HRT outcomes when initiated under age 60(Data from 3,310 women in WHI Study) ESTROGEN ONLY 10,000 Women Years Pulmonary Embolism 1 Increase 2 Stroke 3 Total Deaths Decrease 8 Breast Cancer 11 CVD . . . . . . . . 22 59 22 Diabetes 56 All Fractures MacLennan

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