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Blood

Blood. Components of Blood. Whole blood RBCs WBCs Platelets: cell fragments that aid in clotting Plasma 90% water (allows materials to dissolve) Amino acids, glucose, hormones, vitamins, salts, waste Concentrations allows diffusion in/out of blood stream. Red Blood Cells.

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Blood

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  1. Blood

  2. Components of Blood • Whole blood • RBCs • WBCs • Platelets: cell fragments that aid in clotting • Plasma • 90% water (allows materials to dissolve) • Amino acids, glucose, hormones, vitamins, salts, waste • Concentrations allows diffusion in/out of blood stream

  3. Red Blood Cells • Job: Transport O2 to cells • Produced from stem cells in bone marrow • Dead RBC’s filtered by liver & spleen and combine with poop

  4. Sickle Cell Normal

  5. White Blood Cells • Job: Kill foreign invaders & dead cells • Able to move through tissue to swallow invaders

  6. Platelets • Job: Help form clots to stop bleeding • Proteins form a web to trap cells & platelets

  7. ABO Blood Groups • Antigens: • Proteins on RBC’s that determine your blood type • Help to identify cells as foreign or natural • Analogy: Antigens are like jersey’s • Antibodies: • Part of your immune system • Float freely in plasma • Job: attack foreign antigens

  8. What would happen if a virus with B antigens entered your blood? Your B antibodies will attack and kill this virus. Group A blood Vein • RBC’s have the A antigens on their surface • B antibodies in your plasma • only attack invaders with B antigens B antibody B antibody B antibody B antibody

  9. Key Point:Antibodies attack antigens

  10. Your B antibodies will attack, and cause clots to form. This person will die. What would happen if you gave this person type B blood? Group A blood Vein • RBC’s have the A antigens on their surface • B antibodies in your plasma • only attack invaders with B antigens B antibody B antibody B antibody B antibody

  11. Key Point:Antibodies attack antigens

  12. What would happen if a virus with A antigens invaded your blood? The A antibodies would attack and kill the virus. Group B blood Vein • RBC’s have B antigens on their surface • A antibodies in your blood plasma • only attack invaders with A antigens A antibody A antibody A antibody A antibody

  13. Key Point:Antibodies attack antigens

  14. Their A antibodies would attack the donated blood, causing blood clots. This person would die. What would happen if this person was given type A blood during a transfusion? Group B blood Vein A antibody • RBC’s have B antigens on their surface • A antibodies in your blood plasma • only attack invaders with A antigens A antibody A antibody A antibody

  15. Key Point:Antibodies attack antigens

  16. What would happen if this person was invaded by the viruses below? They do not have antibodies to attack these viruses. Group AB blood Vein • RBC’s have both A & B antigens on their surface • Neither A or B antibodies in your blood plasma Can you predict the antibodies they will have?

  17. Nothing bad would happen. They have no antibodies to attack this blood. Nothing bad would happen. They have no antibodies to attack this blood. What would happen if you gave this person type B blood? What would happen if you gave this person type A blood? Group AB blood Vein • RBC’s have both A & B antigens on their surface • Neither A or B antibodies in your blood plasma

  18. The antibodies would attack and kill the viruses. What would happen if this person was invaded by the viruses below? Group O blood Vein • Neither A or B antigens on the surface of your RBCs • Both A & B antibodies in your plasma • will attack invaders with A or B antigens A antibody A antibody B antibody B antibody Can you predict the antibodies they will have?

  19. Key Point:Antibodies attack antigens

  20. The A antibodies will attack, causing blood clots. This person will die. What would happen if you gave this person type A blood? Group O blood Vein • Neither A or B antigens on the surface of your RBCs • Both A & B antibodies in your plasma • will attack invaders with A or B antigens A antibody A antibody B antibody B antibody

  21. Key Point:Antibodies attack antigens

  22. The B antibodies will attack, causing blood clots. This person will die. What would happen if you gave this person type B blood? Group O blood Vein • Neither A or B antigens on the surface of your RBCs • Both A & B antibodies in your plasma • will attack invaders with A or B antigens A antibody A antibody B antibody B antibody

  23. Key Point:Antibodies attack antigens

  24. Both the A and B antibodies will attack, causing blood clots. This person will die. What would happen if you gave this person type AB blood? Group O blood Vein • Neither A or B antigens on the surface of your RBCs • Both A & B antibodies in your plasma • will attack invaders with A or B antigens A antibody A antibody B antibody B antibody

  25. Key Point:Antibodies attack antigens

  26. If you have type A blood, can you receive: Type A blood? Type B blood? Type AB blood? Type O blood? Yes No No Yes B antibodies will attack any blood with B antigens.

  27. If you have type B blood, can you receive: Type B blood? Type A blood? Type AB blood? Type O blood? Yes No No Yes A antibodies will attack any blood with A antigens.

  28. If you have type AB blood, can you receive: Type AB blood? Type A blood? Type B blood? Type O blood? Yes Yes Yes Yes They have neither A nor B antibodies.

  29. If you have type O blood, can you receive: Type O blood? Type A blood? Type B blood? Type AB blood? Yes No No No A antibodies will attack any blood with A antigens. B antibodies will attack any blood with B antigens.

  30. Rh Factors • If Rh+ • Cells contain the Rh antigen • Can receive Rh+ or Rh- blood • If Rh- • Cells lack the Rh antigen • Plasma contains Rh antibody • Only receive Rh- blood

  31. Francis was just in a bad accident and lost a lot of blood. He is blood type B+. Can you help save him?

  32. Blood type B+ Antigens: Which does he have? A B Rh Antibodies: Which does he have? A B Rh

  33. Francis has B+ blood type because of the B and Rh antigens. If he is given B+ blood in a transfusion… Will his antibodies attack this blood? No. His A antibodies only attack A antigens. Can he receive B+ blood? Yes. Vein A antibody A antibody A antibody

  34. Francis has B+ blood type because of the B and Rh antigens. If he is given B- blood in a transfusion… Will his antibodies attack this blood? No. His A antibodies only attack A antigens. Can he receive B- blood? Yes. Vein A antibody A antibody A antibody

  35. Francis has B+ blood type because of the B and Rh antigens. If he is given A+ blood in a transfusion… Will his antibodies attack this blood? Yes. His A antibodies will attack the A antigens. Can he receive A+ blood? No. Agglutination: clumping of the blood Vein A antibody A antibody A antibody

  36. Francis has B+ blood type because of the B and Rh antigens. If he is given A- blood in a transfusion… Will his antibodies attack this blood? Yes. His A antibodies will attack the A antigens. Can he receive A- blood? No. Agglutination: clumping of the blood Vein A antibody A antibody A antibody

  37. Francis has B+ blood type because of the B and Rh antigens. If he is given AB+ blood in a transfusion… Will his antibodies attack this blood? Yes. His A antibodies will attack the A antigens. Can he receive AB+ blood? No. Agglutination: clumping of the blood Vein A antibody A antibody A antibody

  38. Francis has B+ blood type because of the B and Rh antigens. If he is given AB- blood in a transfusion… Will his antibodies attack this blood? Yes. His A antibodies will attack the A antigens. Can he receive AB- blood? No. Agglutination: clumping of the blood Vein A antibody A antibody A antibody

  39. Francis has B+ blood type because of the B and Rh antigens. If he is given O+ blood in a transfusion… Will his antibodies attack this blood? No. His A antibodies only attack A antigens. Can he receive O+ blood? Yes. Vein A antibody A antibody A antibody

  40. Francis has B+ blood type because of the B and Rh antigens. If he is given O- blood in a transfusion… Will his antibodies attack this blood? No. His A antibodies only attack A antigens. Can he receive O- blood? Yes. Vein A antibody A antibody A antibody

  41. Sebastian was just involved in an accident at work and lost a lot of blood. He is blood type A-. Can you help save him?

  42. Blood type A- Antigens: Which does he have? A B Rh Antibodies: Which does he have? A B Rh

  43. Sebastian has A- blood type because of the A antigen. If he is given A- blood in a transfusion… Will his antibodies attack this blood? No. His B and Rh antibodies only attack B and Rh antigens. Can he receive A- blood? Yes. Vein B antibody Rh antibody Rh antibody B antibody B antibody Rh antibody

  44. Sebastian has A- blood type because of the A antigen. If he is given A+ blood in a transfusion… Will his antibodies attack this blood? Yes. His Rh antibodies will attack the donated Rh antigens. Can he receive A+ blood? No. Agglutination: clumping of the blood Vein B antibody Rh antibody Rh antibody B antibody B antibody Rh antibody

  45. Sebastian has A- blood type because of the A antigen. If he is given B- blood in a transfusion… Will his antibodies attack this blood? Yes. His B antibodies will attack the donated B antigens. Can he receive B- blood? No. Agglutination: clumping of the blood Vein B antibody Rh antibody Rh antibody B antibody B antibody Rh antibody

  46. Sebastian has A- blood type because of the A antigen. If he is given B+ blood in a transfusion… Will his antibodies attack this blood? Yes. Both his B and Rh antibodies will attack the donated B an Rh antigens. Can he receive B+ blood? No. Agglutination: clumping of the blood Vein B antibody Rh antibody Rh antibody B antibody B antibody Rh antibody

  47. Sebastian has A- blood type because of the A antigen. If he is given AB- blood in a transfusion… Will his antibodies attack this blood? Yes. His B antibodies will attack the donated B antigens. Can he receive AB- blood? No. Agglutination: clumping of the blood Vein B antibody Rh antibody Rh antibody B antibody B antibody Rh antibody

  48. Sebastian has A- blood type because of the A antigen. If he is given AB+ blood in a transfusion… Will his antibodies attack this blood? Yes. Both his B and Rh antibodies will attack the donated B and Rh antigens. Can he receive AB+ blood? No. Agglutination: clumping of the blood Vein B antibody Rh antibody Rh antibody B antibody B antibody Rh antibody

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