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SUNY Research UB-SUNY Participants Department of Microbiology & Immunology

SUNY Research UB-SUNY Participants Department of Microbiology & Immunology. The basic science microbiology department within the UB School of Medicine & Biomedical Sciences The only dedicated microbiology department at UB SUNY 15 primary faculty (with 2 on the way)

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SUNY Research UB-SUNY Participants Department of Microbiology & Immunology

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  1. SUNY Research UB-SUNY Participants Department of Microbiology & Immunology • The basic science microbiology department within the UB School of Medicine & Biomedical Sciences • The only dedicated microbiology department at UB SUNY • 15 primary faculty (with 2 on the way) • Funded research programs in virology, immunology, bacterial & eukaryotic pathogens • Home of the Witebsky for Microbial Pathogenesis & Immunology comprising >24 investigators across the UB Medical Campus

  2. PieroBianco, Ph.D., Assoc. Prof. Department of Microbiology & Immunology Contact: pbianco@buffalo.edu • DNA repair and replication • Role of essential single-stranded DNA binding protein (SSB) • SSB interactome as a novel drug target(s) • Single molecule approaches: atomic force, optical tweezers, microfluidics

  3. Jay Bangs, Ph.D., Professor & Chair Department of Microbiology & Immunology Contact: jdbangs@buffalo.edu • Molecular parasitology: African trypanosomes • Secretory transport of GPI-anchored proteins • Lysosomal and endosomal function and biogenesis • Sphingolipid metabolism as a novel drug target(s) • Integrated cell biology, biochemistry & glycobiology approaches

  4. Tony Campagnari, Ph.D., Professor Department of Microbiology & Immunology Contact: acc@buffalo.edu • Bacterial pathogenesis (Gram Negatives): Morexellacatarrhalis & Actinobacterbaumannii • Virulence determinants in adherence and biofilm formation • Morexella(otitis media): adhesins as novel vaccine targets • Actinobacter(nosocomial infections): role of surface glycoconjugates in attachment and persistence • Novel therapeutics for drug resistant infections: photodynamic therapy & electrostimulation

  5. Tony Connell, Ph.D., Professor Department of Microbiology & Immunology Contact: connell@buffalo.edu • Bacterial pathogenesis & immunology • Type II enterotoxins: immunomodulation & potential as systemic & mucosal adjuvants • Aggregative invasive E. coli (AIEC): association with irritable bowel & Crohn’s diseases • Iron acquisition by Bordetellasps • Morexellasps: vaccine development for cattle pathogens

  6. Anders Hakansson, Ph.D., Assist. Professor Department of Microbiology & Immunology Contact: andersh@buffalo.edu • Pathogenesis and innate immunity in pneumococcal disease – nasopharyngial and inner ear infections • In vitro & in vivo studies of colonization & biofilm formation • Augmentation of drug resistance by biofilms • HAMLET: a protein:lipid innate immune complex from human milk • Apotosis-like killing of pneumococci; synergistic killing of drug resistant bacteria

  7. Tom Melendy, Ph.D., Assoc. Professor Department of Microbiology & Immunology Contact: tmelendy@buffalo.edu • Molecular virology: small DNA tumor viruses; papilloma/polyoma • Interaction of viral & host replication factors • Specifically - recruitment of host factors by viral replicases (HPV E1; SV40 large T antigen) • Viral responses to DNA damage

  8. John Panepinto, Ph.D., Assist. Professor Department of Microbiology & Immunology Contact: jcp25@buffalo.edu • Mycology and fungal pathogenesis • Adaptation to host environment: mechanisms of post- transcriptional gene regulation • RNA binding proteins & deadenylation dependent RNA turnover • Nucleotide metabolism as drug target(s): reduced RNA degradation  reduced nucleotide pools  reduced virulence & increased drug sensitivity

  9. Yijun Sun, Ph.D., Assist. Professor Department of Microbiology & Immunology NYS COE in Bioinformatics & Life Sciences Contact: yijunsun@buffalo.edu • Computational biology & bioinformatics • Microbial and cancer informatics & metagenomics • Developing new algorithms and infrastructures for managing & exploiting honking big datasets!

  10. SUNY Research Absentee Participants Department of Microbiology & Immunology • Dick Bankert, PhD, Professor: Tumor immunology • Laurie Read, PhD, Professor: Molecular parasitology, African trypanosomes, RNA editing, arginine methylation • Mike Russell, PhD. Professor: Gonococcal pathogenesis, mucosal immunity, vaccine development • Noreen Williams, PhD, Prof.: Molecular parasitology, African trypanosomes, ribosomal biogenesis, mitochondrial bioenergetics

  11. SUNY Research Future Participants Department of Microbiology & Immunology • Ira Blader, PhD, Assoc. Prof.: Molecular parasitology, Toxoplasma, host:parasite interactions, retinitis • Beth Wohlfert, Assist. Prof: Mucosal immunology, T-cell regulation, memory & differentiation, Toxoplasma &Heligmosomoides

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