Global Healthy Living Foundation Capabilities Overview

1. Global Healthy Living Foundation Capabilities Overview March 7, 2007

2. Presentation Outline • Funding organization’s needs • Channel patient awareness to drive education • Diagnosis • ICAP: Improve compliance, adherence and persistency among existing users • Sequence - GHLF positioning • Drug approval • Physician education • Structured supporting stabilizers - GHLF expertise • Healthy Living Forum (Community-based programs) • Physician advisory board meetings • ICAP activities* • Minority outreach • Continuity • Preserve and enhance ongoing outreach • Incorporate existing programs • Increase disease state awareness message depth

3. Overview: GHLF Disease-state sites • 515 N. Midland Ave.Upper Nyack, NY 10960 Global Healthy Living Foundation • Seestrasse 73CH-8702 Zurich, Switzerland • Brands managed by people with the disease. Not all brands are shown.

4. Asthma/COPD Arthritis Psoriasis Diabetes/DPNP Sleep Disorders Cancer HIV Children’s diseases Heart diseases Cholesterol/Hypertension Depression/Anxiety Obesity Irritable Bowel Disease Sickle Cell Disease Erectile Dysfunction Osteoporosis (bone health) BPH Overview: Chronic Disease Specialties

5. Overview: About GHLF • Mission Statement • We protect the value of existing health awareness messages and extend the foundation to drive patients to lead healthier lifestyles by incorporating diet, exercise, a positive mental outlook, and the proper drug therapy. • We improve the quality of life for people with chronic diseases. • We focus on patients, caregivers and healthcare professionals. • We aspire to change the long-term identity from chronically ill to empowered, healthy patients. • Niche Capabilities • Hispanic, Asian, Asian Indian, African American and GLBT community outreach programs with cultural and language sensitivities.

6. Outcomes and Strategies • Possible Program Outcomes • Increase awareness • Increase diagnosis • Sustain long term commitment to a healthy life compliantly and persistently • Typical Strategies • Leverage GHLF’s reach, reputation and experience to increase/generate disease awareness and education • Initiate/continue dialogue with audience, begin with registration and profiling • Educate users with messaging designed to motivate compliance • Promote long-term patient relationships with continued presence and support at events

7. The Doctor-Patient Formula Patient Recruitment Physicians Members Advocacy groups Local/state government Community centers Religious/civic organizations

8. Program Overview: What are Healthy Living Forums? • GHLF organizes and executes local patient events called Healthy Living Forums in community centers. • We bring together patients and their caregivers in an entertaining environment for symptom management including exercise, nutrition, motivation. • Partnerships with local patient/consumer groups. • Day or half day workshops provide participants with information about: • Treatment options allotting time for Q&A • Exercise (with emphasis on swimming and water aerobic movement) • Nutrition • Positive mental outlook • Relaxation/meditation techniques

9. Organizing Healthy Living Forums • Outreach to patient groups with event details • Physician speakers • Exercise physiologists • Psychologist presentation • Nutrition seminar • Central location • Meal(s) included • Medically-relevant inexpensive gifts • Free of charge • Pre-registration required • Transportation provided from surrounding areas to central location • Outreach to physicians treating patient groups • Advisory boards with local treating physicians for event content input • Honorariums for event participation • Use of key opinion leaders • Physician contact includes names provided by patient groups • Outreach integrated with representative-physician contact • Partnership with local teaching hospital/medical center • Grand rounds • Venue for patient event

10. Surround-Sound Reach—Patient • Level 1 • Local Patient Groups • Doctor Recommendation • Direct Mail • Word-of-mouth • Email • Website Announcements • Chat Rooms • Message Boards • Level 3 • Healthy Living Forums • Educational Materials Distribution • Level 4 • Follow-up programs • Level 2 • Community Centers • Retirement Centers/Communities • Doctor’s Offices • Local Elected/Appointed Officials • Municipal Health Departments • Churches/Synagogues/Mosques • Support Groups • Fraternal Organizations • Health Clubs • Local Universities/Colleges • Teaching Hospitals • Level 5 • National/Local Exercise Association(s) • Total Immersion Swimming • Advertising • Publicity

11. Surround-Sound Reach—Professional • Level 1 • Local physician’s advisory board meetings • Educational materials distribution • Physician networking • Level 2 • Dedicated/Customized Physician/Healthcare provider web site • Level 3 • University/college medical and healthcare associations • Board of institutions • Local professional societies

12. Program Overview: Swimming Sample swim program agenda: 7:30–8:00 A.M. Check-In and continental breakfast, distribution of medically relevant items 8:00–8:30 Welcome addresslocal patient advocate moderator 8:30–9:00 Land exercises and pool warm-up (certified swim coaches) 9:00–9:15 Change for pool 9:15–10:15 Water instructionVertical swimming, horizontal swimming, range-of-motion 10:15–10:30 Change, return for presentation 10:30–11:15 Presentation by MD 11:15–12:00 Lunch 12:00–12:30 P.M.The Healing Partnership Between You and Your Chronic DiseaseLaurie Ferguson, PhD 12:30–12:45 Reflections and farewell

13. Program Overview: Healthy Living Forum Sample Healthy Living Forum agenda: 7:30-8:00 A.M. Check-in and continental breakfast, distribution of medically relevant items 8:00–8:30 Welcome addresslocal patient advocate moderator 8:30-8:45 Stretching and warm up by local exercise physiologist 8:45-9:30 Physician presentation—Diagnosing,Treating and Living with (disease) 9:30-9:45 Range of motion exercise demonstration 9:45-10:15 The Healing Partnership Between You and Your (disease)Laurie Ferguson, PhD. 10:15-10:30 Reflections and farewell

14. Program Overview: ICAP (Improving Compliance, Adherence & Persistence) • Keeping patients motivated after – or in between – events • Certificate of participation/thank you letter • Virtual exercise clubs • Online clubs that encourage exercise and allow patients to report their exercise success • Birthday cards • GHLF sends out birthday cards to registered patients(year long activity) • Photo competition • Where in the world are our patients? Patients send photos of themselves on vacation with their certificate of participation • Conference calls • Patients dial a toll-free number and have the ability to join a number of conference calls with medical professionals

15. Program Overview: ICAP (Continued) • Monthly E-newsletter • The monthly newsletter informs members of up to date news regarding their disease, birthday wishes, activity reminders, advice column, updates on patients’ progress with virtual exercise clubs, etc. • Micro Grants • Micro Grants encourage people to continue practicing the healthy lifestyle they learned at an event. • Mentoring • Mentors with the disease are trained to lead and grow groups. • Mentors advance in a master path, and are rewarded with conference attendance and education.

16. Program Overview: Physician ICAP • Keeping healthcare providers informed after – or in between – events • Continuous healthcare provider communication • Advise doctors how their recommendations were implemented into the patient events (based on focus group worksheet). • Patient Update • Anytime a patient makes changes on the virtual exercise club their healthcare provider is automatically notified via email. • Event Notification • Notify healthcare providers of upcoming patient events via email and invitation • Program support • Integrating existing healthcare provider ICAP • Integrating existing patient ICAP

17. Indianapolis Patient Event • Blended with Healthy Horizons and Lilly grant to demonstrate momentum and create a learning experience for the long-term longitudinal study. • Logistics • Brookside Community Center • September 1, 2007 • “Growing Older and Staying Healthy” • Arthritis, hypertension, diabetes, cardiovascular (cholesterol), acid reflux, obesity, asthma • Physician, psychologist, exercise physiologist, nutritionist, moderator, Butler faculty • Faculty and student experiential learning • Data collection and analysis to confirm longitudinal study direction • Community outreach • Promotion, publicity • Market research • Additional opportunities? • Shared costs

18. Next Steps • Parallel development tracks: • September 1 patient event • Butler/GHLF grant preparation • September 1 patient event • GHLF responsibility • Butler learning experience • Butler/GHLF grant preparation • Create core committee • Determine demographics (audience, disease) and mission • Create timetable and budget • Identify foundation partners • Study parameters • Schedule next meeting

19. Appendix

20. Appendix I: GHLF Board of Advisors • Rhoda Green, PhD • Thomas Lehman, MD • Mark Young, MD • Bryan O’Young, MD • Barry Schoenberg, DPM • Howard Schertzinger, MD • Joel Silverfield, MD • Deborah Chase • John Dickson, MD • Locally constituted medical boards of advisors

21. Appendix I: GHLF Board of Directors • I. Elaine Allen, Professor, Babson College, Babson Park, MA • Ward White, Director, The Marcus Foundation, Milwaukee, WI • Jack Finnegan, President, The MacGregor Group, Pine Brook, NJ • David Wolf, Esq., Cowan DeBeats Abrahams & Sheppard, New York, NY • Richard Fetter, Dean, College of Business Administration, Butler University, Indianapolis, IN • Seth Ginsberg, Co-founder, GHLF, New York, NY

22. Dr. Robert Abdoo, New York Dr. Emmanuel Akinwuntan, Leuven, Belgium Dr. Gülseren Akyüz, Istanbul Dra. Jacqueline Dote Araya, Santiago Dr. Caroline Barmatz, Tel Aviv Dr. Hugo Nuñez Bernadet, Punta Del Este, Uruguay Dr. David Cassius, Seattle Dr. Lesley Castro (Ph.D), San Diego Dr. Gerardo I. Correa, Santiago Dr. Veronica Rodriguez de la Cruz, San Juan Dr. Jeff Davis, Birmingham Dr. Yohann D. Delarue, Paris Dr. Peter Disler, Melbourne Dr. John Dickson, London Dr. Keith Feder, Los Angeles Dr. Laurie Ferguson (Ph.D.), New York Dr. Andrew Frank (Ph.D.), London Dr. Rhoda Frindell Green (Ph.D.), New York Dr. John Goldman, Atlanta Dr. Viktor Gribenko, New York Dr. Matthew Heller, Boston Dr. Rafi Heruti, Tel Aviv Dr. Abdellah Hocini, Valenton, France Dra. Marta Imanura, São Paulo Dr. Shin-Ichi Izumi, Tokyo Dr. Brinda Kantha, Philadelphia Dr. Alvydas Juocevicius, Vilnius, Lithuania Dr. Miloslav Kadlec, Prague Dra. Christianne Akie Kavamoto, São Paulo Dr. Stoyan Kemerov, Plovdiv, Bulgaria Dr. Jong-Moon Kim, Buk-Do, South Korea Dr. Stanley Kornhauser (Ph.D.), New York Dr. Thomas Lehman, New York Dr. Roger Levi, Rio de Janiero Dr. Jef Lieberman, Atlanta Dr. Rodriguez Mariu, Madrid Dr. Mark Medici, New York Dr. John Markenson, New York Dr. Zaliha Omar, Kuala Lampur Dr. Bryan O’Young, New York Dr. Eliott Pellman, New York Dr. Ernesto Candau Pérez, Madrid Dr. Bouathep Phoumindr, Vientiane, Laos Dr. Ted Pincus, Vanderbilt University Dra. Joyce Bolaños de Rodríguez, Caracas, Venezuela Dr. Alvydas Rudokas, Vilnius, Lithuania Dra. Marta Saad, São Paulo Dr. Howard Scherzinger, Cincinnati Dr. Sergio Schwartzman, New York Dr. Herschell Servies, Indianapolis Dr. David Silver, Los Angeles Dr. John Siffri, Charlotte Dr. John Stuart, Memphis Dr. Gerold Stucki, Munich Dr. Than Toe, Myanmar Dr. David Yocum, Tucson Dr. Mark Young, Baltimore Appendix II: GHLF Affiliated Professionals

23. Appendix III: GHLF Board of Institutions • Royal College of Physicians, London • Columbia Presbyterian Hospital, New York • Hospital for Special Surgery, New York • Weill Medical College of Cornell University, New York • Long Island Jewish Medical Center, New York • Maryland Rehabilitation Center, Baltimore • Johns Hopkins School of Medicine, Baltimore • Metropolitan Atlanta Rheumatology Society, Atlanta • New York College of Podiatric Medicine, New York • Phelps Memorial Hospital, New York • University of Utah Medical Center, Salt Lake City • St. Francis Hospital, Hartford, Conn. • Mt. Sinai Medical Center, New York

24. Appendix IV: Bios • Louis Tharp, Executive Director and Co-Founder After running a successful international public relations, advertising and marketing company for nearly 20 years, and working for some of the largest international PR and marketing agencies, Louis Tharp became a social entrepreneur in 1999, co-founded, and acted as venture capitalist for CreakyJoints, an international service organization for people with arthritis. Today, CreakyJoints is a division of GHLF, which also includes other disease-state groups. Mr. Tharp was previously a contract writer for the New York Times as well as other daily newspapers, and published his first hardcover book, The Complete Manager's Guide to Promotional Merchandise (Dow-Jones Irwin) in 1989. Mr. Tharp is a competitive swimmer and is the swim coach for the U.S. Military Academy Triathlon team at West Point, NY. He serves on the board of visitors for the College of Business at Butler University, Indianapolis where he graduated with a B.S. in Journalism in 1972. • Seth Ginsberg, Board Member and Co-Founder Seth Ginsberg was diagnosed at age 13 with Spondyloarthropathy, a degenerative form of arthritis. He co-founded CreakyJoints at the age of 18, in order to help fellow arthritis sufferers understand the benefits of exercise, diet, a positive mental outlook, and a productive relationship with their doctor. Today, CreakyJoints is a division of GHLF, which also includes other disease-state groups.. Mr. Ginsberg graduated from Babson College, Boston, with a B.S. in Social Entrepreneurship in 2003.. He is a former board member of the Westchester Arthritis Foundation and spokesperson for the NationalArthritis Foundation.

25. Appendix IV: Bios (continued) • Richard Tjoa, Client Service & Technology Vice President Richard Tjoa oversees technology implementation and growth at GHLF, including multi-language patient and physician websites. He graduated from the University of California at Berkeley with a B.S. in Electrical Engineering and Computer Science and was one of two in his graduating class to earn the Kennedy Interdisciplinary Studies Award where he worked in the field of American Government and Institutions. • Laurie Ferguson, Ph.D., Vice President of Research and Education Dr. Ferguson received her Ph.D. in Psychology from the Derner Institute at Adelphi University, New York in 2004. She is a frequent speaker at CreakyJoints events and leads GHLF research. She was a founding professional of the Exhale Foundation, graduated cum laude with high honors from Smith College, and received her Masters of Divinity from Princeton Seminary.

26. Appendix IV: Bios (continued) • Marco Pilloud, Managing Director, Europe  Marco Pilloud, based in Zurich, began as Managing Director, Europe of CreakyJoints in 2000 and was named to lead GHLF in Europe in 2004. He was formerly Area Manager of the Swiss Business Unit of Computer Sciences Corporation, and Key Account Manager with UBS Swiss Life. Mr. Pilloud received his B.A. in International Affairs in 1991 from George Washington University in Washington, D.C. and his MBA in International Business in 1995 from Sacred Heart University, Luxembourg. He participated in the World Swimming Championships for Luxembourg in 1991, and continues to swim and coach in Zurich. • Stefan Bill, Program Associate Stefan Bill graduated from Berufsschule Burgdorf, Burgdorf, Switzerland in 2004, and is responsible for event organization and administration for European programs. He is fluent in English, Swiss German and High German. A nationally and internationally recognized competitive swimmer, Mr. Bill uses his coaching and swimming expertise in the CreakyJoints A-Games as a lecturer and instructor.