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Current studies and services

Rakai Health Sciences Program (RHSP) Uganda 1988-2011 Population-based Research on HIV, other Infectious Diseases, Reproductive Health and Service delivery. Current studies and services. Research studies RCCS and nested studies Circum and related studies

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Current studies and services

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  1. Rakai Health Sciences Program (RHSP) Uganda1988-2011Population-based Research on HIV, other Infectious Diseases, Reproductive Health and Service delivery

  2. Current studies and services • Research studies • RCCS and nested studies • Circum and related studies • Acyclovir prophylaxis in HIV-1/HSV-2 co-infected patients • Rakai Youth Project • Malaria-Home and facility based surveillance • Other lab-based studies • Services alongside research • HIV/AIDS care and treatment • HIV Pre-ARV • HIV antiretroviral therapy • pMTCT • General Health Care (Mobile & static) • Male circum roll out and training • Health Education • Voluntary HIV testing and counseling

  3. RHSP HIV/AIDS Care Program • Since June 2004 has provided HIV/AIDS Care to approximately 5600 clients • Enrollment through RCCS and Walk-in until 2008 • Until January 2011 all clients received CD4 and HIV VL monitoring every 6 months, now performed annually due to budget issues • Clinical and laboratory data maintained in database at RHSP headquarters

  4. HIV/AIDS Care (ARV) Numbers

  5. Home Based Malaria Surveillance • Funded by Division of Intramural Research, NIAID/NIH • Active home based monthly surveillance of 360 households, approximately 1700 individuals in 2 Rakai communities • Focus on malaria rates among children (6 months-10 years) and adult caregivers • Initiated April 2011

  6. Home-based Malaria Progress • Two communities from each of 2 clusters • 2 high and 2 low malaria endemic communities • Enrollment completed in 40 homes • 152 Adult and children clients so far enrolled • Rapid diagnostic testing done on all febrile participants to determine immediate need for treatment, blood smear done on all participants

  7. IeDEA Facility Based Malaria Study • Objectives • To estimate the proportion of febrile illnesses (body temperature >=380c) with malaria parasites on a blood smear among all patients presenting to outpatient clinic at Kalisizo hospital • To estimate the prevalence, presentation, and treatment outcomes of severe malaria amongst HIV-infected and uninfected children aged <5 years admitted to Kalisizo and Bikira hospitals in Rakai district, Uganda.

  8. IeDEA Facility Based Malaria Study • Retrospective review of all lab records at 2 health facilities to answer first objective • Prospective enrollment of 3000 children less than 5 years and the same facilities to measure the prevalence of outpatient malaria, presentation and outcomes • Planned to start enrollment week of May 9th 2011

  9. IeDEA Facility Based Malaria Study Progress • All IRB approvals (UVRI-SEC, UNCST & WIRB-Indiana) obtained and on file • 4 Lab techs trained in Kisumu; to re-train in few months • Protocol discussion & training with facility staff & RHSP • GCP training for facility based staff in April 2011 • HSP re-training for all staff on IeDEA • Supplies delivered to facilities • Enrollment to start Monday May 16th 2011

  10. IeDEA Facility Based Malaria Study Challenges • Facility based staff transferred frequently – requires training and re-training • Poor record keeping– Introduced and trained methods of records management

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