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Supporting Information for G- quadruplexes within prion mRNA: the missing link in prion disease?

Supporting Information for G- quadruplexes within prion mRNA: the missing link in prion disease? René C.L. Olsthoorn , Leiden Institute of Chemistry, Leiden University, Gorlaeus Laboratories, Einsteinweg 55, 2333CC Leiden, The Netherlands . E-mail : olsthoor@chem.leidenuniv.nl.

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Supporting Information for G- quadruplexes within prion mRNA: the missing link in prion disease?

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  1. Supporting Information for G-quadruplexes within prion mRNA: the missing link in prion disease? René C.L. Olsthoorn, Leiden Institute of Chemistry, Leiden University, Gorlaeus Laboratories, Einsteinweg 55, 2333CC Leiden, The Netherlands.E-mail: olsthoor@chem.leidenuniv.nl

  2. Normalized absorbance Temperature (ºC) Figure. S2. Absorbance profiles at 295 nm of the reference RNA Pri-Qd in PBS (137 mM NaCl, 2.7 mMKCl, 10 mM Na2HPO4, 2 mM KH2PO4 pH 7.4) without (blue curve) and with 100 mMKCl (red curve). Figure S1. Absorbance profile at 295 nm of the reference RNA hairpin Pri-Hp in 10 mM sodium phosphate buffer (pH6.7) and 50 mMKCl.

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