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Division of Yonsei Dental Sciences

Division of Yonsei Dental Sciences. ○ Vision And Objectives. “Yonsei Standing Proud”. Through the Global 5-5-10 Project for Division of Dental Sciences, Yonsei University School of Dentistry will become one of the world’s leading educational and research institutes.

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Division of Yonsei Dental Sciences

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  1. Division of Yonsei Dental Sciences

  2. ○ Vision And Objectives “Yonsei Standing Proud” Through the Global 5-5-10Project for Division ofDental Sciences, Yonsei University School of Dentistry will become one of the world’s leading educational and research institutes.

  3. ○ Organization and Participants

  4. ○ Organization and Participants

  5. ○ Research Fields • ● Cell signaling • - Cell signaling associated with bone formation • Development of drugs that induce bone formation and • prevent bone absorption Cell Signaling in Bone cells ▶ Cell signaling associated with bone remodeling ▶ Development of drugs to induce bone formation and prevent bone resorption

  6. ○ Research Fields • ● Tissue regeneration • Artificial tooth and bone formation • using organ culture system • Orofacial hard tissue regeneration • with an aid of artificial teeth and • bones ▶ Construction of artificial tooth and periodontium

  7. ○ Research Fields ● Development of dental materials and medical devices ▶ Development and application of bioceramics for bone replacement ▶ Development of new dental casting metals ● Digital imaging ▶ Development of diagnosis technique using digital image ▶ Data analysis using 3-D image

  8. ○ Research Fields ● Periodontal disease and immune system ▶ Treatment and prevention of periodontal disease ▶ Drug development inducing periodontal tissue regeneration ● Carcinogenesis and cancer prevention ▶ Research on the carcinogenesis ▶ Mechanism of Carcinogenesis ▶ Drug development for cancer treatment and prevention

  9. ○ Activities and Outputs ● Activities Student exchange program ▶ Tokyo Dental college ▶ UCLA ▶ University of Pennsylvania ▶ Tuft University ● Outputs ▶ Molecular interactions between Tbx3 and Bmp4 and a model for dorsoventral positioning of mammary gland development. Proc Natl Acad Sci USA, 103(45):16788-16793, 2006 ▶A Wnt-Axin2-GSK3 cascade regulates Snail activity in breast cancer cells. Nature Cell Biology. 8(12):1398-1406, 2006 ▶Xanthorrhizol inhibits 12-0-tetradecanoylphobol-13-acetate-induced acute inflammation and two-stage mouse skin carcinigenesis by blocking the expression of ornithine decarboxylase, caclooxygenase-2 and inducible nitric oxide synthase through mitogen-activated protein kinases and/or the nucleas factor-kappa B. Carcinogenesis. 28(6):1224-1231, 2007 ▶Skeletal muscle dressed in SOCs. Nature Cell Biology. 10(6):639-641, 2008

  10. ○ Contact Point ● Director: Syng-Ill Lee, D.D.S., Ph.D. ● Address: Department of Oral Biology, Yonsei University College of Dentistry 134 Shinchon-dong, Seodaemun-gu, Seoul 120-752, Korea ● Tel: +82-2-2228-3052 Fax: +82-2-364-1085 ● E - mail: lsi@yuhs.ac Website:http://bk21-dentsci.yonsei.ac.kr

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