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Alzheimer’s Disease

Alzheimer’s Disease. By: Chelcy Branon. Facts. In 2006, there were 26.6 million sufferers worldwide Costs 100 billion dollars per year. 2 Types of AD. Early Onset AD: Symptoms before age 60 Much less common (5%); but gets more severe quicker. Runs in families and through genes.

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Alzheimer’s Disease

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  1. Alzheimer’s Disease By: Chelcy Branon

  2. Facts • In 2006, there were 26.6 million sufferers worldwide • Costs 100 billion dollars per year

  3. 2 Types of AD • Early Onset AD: • Symptoms before age 60 • Much less common (5%); but gets more severe quicker. • Runs in families and through genes. • Late Onset AD: • Symptoms after age 60. • Most common.

  4. Causes of Alzheimer’s • Genetics • Old age • 6th leading cause of death; live about 8 years after diagnosed. • Starts in the learning part of the brain • Scientists believe that AD prevents parts of a cell’s “factory” from running. As the damage spreads, the cells lose their ability and eventually die off. • Plaques and tangles target parts of the brain that affect memory in people with AD.

  5. Causes continued • Loss of neurons and synapses in the cerebral cortext. Causes degeneration of the frontal cortex, temporal lobe and parietal lobe. • Protein misfolding disease caused by the over abundance of abnromally folded amyloid beta and amyloid tau.

  6. Medicine/Treatment • Slow down the progression of the disease. • Manage all symptoms to make everyday life more manageable. • Drug Treatment: • Donepezil and Rivastigmine: Cholinesterase inhibitor that improves mental function. It is a naturally occuring substance in the brain. • Galantamine: Acetylcholinesterase inhibitor that targets memory and thought by increasing a natural substance in the brain. • Memantine: a NMDA receptor antagonist that decreases the abnormal activity in the brain to help people think clearer.

  7. Future • 95% of known information of AD has been found in the last 15 years. • Studies are continuously happening. • FIND A CURE.

  8. Cites • Board, A.D.A.M. Editorial. "Alzheimer's Disease." Alzheimer's Disease. U.S. National Library of Medicine, 26 Sept. 2011. Web. 27 Nov. 2012. <http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001767/>. • "Alzheimer's Disease & Dementia | Alzheimer's Association." Alzheimer's Disease & Dementia | Alzheimer's Association. Alzheimer's Association, n.d. Web. 27 Nov. 2012. <http://www.alz.org/alzheimers_disease_what_is_alzheimers.asp>. • "Alzheimer's Disease." Wikipedia; The Free Encyclopedia. N.p., 27 Nov. 2012. Web. 27 Nov. 2012. <http://en.wikipedia.org/wiki/Alzheimer%27s_disease>. • "Alzheimer's Disease Fact Sheet." National Institute on Aging. Alzheimer's Disease Education and Referral Center, Sept. 2012. Web. 27 Nov. 2012. <http://www.nia.nih.gov/alzheimers/publication/alzheimers-disease-fact-sheet>.

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