40 likes | 205 Views
DNA globule formation with attractive nanoparticles – chromatin conformation. Some ideas for the project. Entropy as the driver of chromosome segregation Suckjoon Jun 1 & Andrew Wright 2 Nature Microbiology, 2010.
E N D
DNA globule formation with attractive nanoparticles – chromatin conformation Some ideas for the project Entropy as the driver of chromosome segregation Suckjoon Jun1 & Andrew Wright2 Nature Microbiology, 2010
Micelle formation by amphiphilic molecules with coarse-grained Lennard-Jones potentials. http://md.chem.rug.nl/cgmartini/index.php/about/martini-projects/sm
r D+2Rg D depletion layer exclusion zone Measuring the entropically-induced potentials between two colloids. Two particles in a polymer solution : Applicable for Polymer approximated as “phantom spheres” Rg/R << 1 cp/cp* << 1 Ideal Solvent 2Rg Asakura & Oosawa, J Polymer Science Vol 33, p. 183 (1958) Verma, Crocker, Yodh, Phys Rev Lett, 81 4004-4007, 1998. Entropy-driven interparticle attraction Approximations not valid for non-dilute mixtures or Rg ~ R
Stability of colloids with DLVO interactions Model the stability of colloidal suspension with Lennard-Jones interactions and electrostatic interactions. With fixed Lennard-Jones parameters (A,B), how does the suspension stability depend on the electrostatic screening length (Debyle length) k-1?