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11.2 Blood: A Fluid Tissue

11.2 Blood: A Fluid Tissue. Pages 482-486. Function of Blood. Delivers oxygen to cells, picks up carbon dioxide Delivers nutrients to cells and collects wastes Temperature regulation Circulation of hormones. Components. Red blood cells White blood cells Platelets Plasma. Plasma.

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11.2 Blood: A Fluid Tissue

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  1. 11.2 Blood: A Fluid Tissue Pages 482-486

  2. Function of Blood • Delivers oxygen to cells, picks up carbon dioxide • Delivers nutrients to cells and collects wastes • Temperature regulation • Circulation of hormones

  3. Components • Red blood cells • White blood cells • Platelets • Plasma

  4. Plasma • 90% water • Dissolved O2, CO2, glucose, vitamins and minerals, wastes • Proteins:for clotting, immunity and water balance • Dissolve ions Na+, K+, Ca2+, Cl-, and HCO3-

  5. Albumins • Control water levels in the blood

  6. Globulins • Transport lipids, cholesterol, fat-soluble vitamins (A,D,E and K), some minerals • Immunoglobulins (antibodies)

  7. Fibrinogen • Role in blood clotting

  8. Serum • Plasma with fibrinogen and clotting factors removed.

  9. Erythrocytes • Red blood cells • Biconcave disks • 135 RBC’s per mm • Formed from stem cells in bone marrow • No nucleus in mature cells • Lifespan 120 days • Liver and spleen break RBC’s down

  10. Leukocytes • White blood cells • nucleus • Granular leukocytes (neutrophils, eosinophils and basophils) kill bacteria • Agranular leukocytes (lymphocytes, monocytes) engulf bacteria • Pus

  11. Granules

  12. Platelets • Protection • Produced in the bone marrow • Blood clotting • Platelets and fibrinogen form clot

  13. Blood Count • Hemocytometer • Anemia (low RBC coun t)

  14. Plasma Plasma 55-58% • Water 91-92% • Plasma proteins 7-8% • Dissolved things 1-2%

  15. Cells • Platelets 250000-300000 per microlitre Leukocytes • Neutrophils 3000-6750 • Lymphocytes 1000-2700 • Monocytes/macrophages 150-720 • Eosinophils 100-360 • Basophils 25-90 • Erythrocytes 4 800 000-5 400 000

  16. Blood Types • Markers A and B • Type A…marker A • Type B…marker B • Type AB…marker A & B • Type O…no marker

  17. Immune response • Transfusions of blood with a different marker causes an immune response

  18. Rhesus Factor • 85% are Rh-positive

  19. Artificial Blood • HBOC hemoglobin-based oxygen carriers • PFCE perfluorocarbon emulsions

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