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Introduction to Microbiology

Introduction to Microbiology. Anas Abu - Humaidan M.D. Ph.D. Lecture 8. Horizontal Gene transfer ( HGT ). Gene transfer / Conjugation. Plasmids. 1-200 kbp of circular dsDNA coding for at least one gene. Plasmids can be a Replicon or epitome.

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Introduction to Microbiology

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  1. Introduction to Microbiology Anas Abu-Humaidan M.D. Ph.D. Lecture 8

  2. Horizontal Gene transfer (HGT)

  3. Gene transfer/ Conjugation

  4. Plasmids • 1-200 kbp of circular dsDNA coding for at least one gene. Plasmids can be a Replicon or epitome. • A mechanism for HGT, many are beneficial, classified according to “conjugativity”, compatibility, function. • Important in transfer of antibiotic resistance and virulence factors.

  5. Plasmids

  6. Plasmids

  7. Gene transfer/ Transduction

  8. Bacteriophages

  9. Gene transfer/ Transformation

  10. Gene transfer/ Transformation

  11. Gene transfer/ Transformation

  12. Gene transfer/ Transposition

  13. Implications of HGT / antibiotic resistance

  14. DNA cloning

  15. Further reading and material: • Murray - Medical Microbiology 8th Edition • Section 4: Bacteriology • Chapter 13: Bacterial metabolisim and genetics • Jawetz, Melnick & Adelberg's Medical Microbiology, 26th edition- Section 1: Fundamentals of Microbiology- • Chapter 7:Microbial genetics • Youtube: • Channel: Judith Leatherman • Video : Bacterial genetics part 1 • Video : Bacterial genetics part 2

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