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Hardy-Weinberg Rule. Allele frequencies when populations are NOT evolving. Hardy-Weinberg Rule. Allele frequencies will NOT change (stay in equilibrium) if the following conditions are met: No mutation Large population isolated from other populations of same species Random mating
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Hardy-Weinberg Rule Allele frequencies when populations are NOT evolving
Hardy-Weinberg Rule • Allele frequencies will NOT change (stay in equilibrium) if the following conditions are met: • No mutation • Large population isolated from other populations of same species • Random mating • Individuals survive and reproduce equally
Hardy-Weinberg Rule • When would we want to know this info? • It provides a yardstick by which changes in allele frequency can be measured. • You can see if a population is evolving
Formula for the allele frequency is p2 + 2pq + q2 = 1 P2 is AA pq is Aa ( x 2 because aA also) q2 is aa You can use the formula to track alleles from one generation to the next to see if the gene frequencies are changing. p= frequency of allele A q= frequency of allele a p+ q = 1 Hardy-Weinberg Rule
Hardy- Weinberg Rule • If you know the percent of homozygous recessive out of the total population, you know q2. Take the square root of it to find q. q is the frequency of a. Then you can find the rest.