1 / 13

Examples of Modeling and Simulating Large-Scale Complex Systems, Processes, and Behaviors

Examples of Modeling and Simulating Large-Scale Complex Systems, Processes, and Behaviors. Mark A. Johnson mark.a.johnson@aero.org. Representative Disciplines. Biochemistry. Biomechanics. Endocrinology. Bioelectricity. Medical Systems. Orthopaedics. Control. Bone Fracture Healing Model.

ingrid-small
Download Presentation

Examples of Modeling and Simulating Large-Scale Complex Systems, Processes, and Behaviors

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Examples of Modeling and Simulating Large-Scale Complex Systems, Processes, and Behaviors Mark A. Johnson mark.a.johnson@aero.org

  2. Representative Disciplines Biochemistry Biomechanics Endocrinology Bioelectricity Medical Systems Orthopaedics Control Bone Fracture Healing Model Physiology Large Scale Systems Visual C++ Systems Integration Unified Modeling Language Soft Computing Object Oriented Systems Engineering Bone Fracture Healing Process

  3. Bone Fracture Healing: Perspectives Overview

  4. Bone Fracture Healing

  5. Bone Fracture Healing OBJECTIVE Develop an Integrated Bioelectrical, Biochemical, and Biomechanical Model of the Bone Fracture Healing Process Sub-Objective Develop a Biochemical Model of the Bone Fracture Healing Process Model Reference Adaptive Control Architecture

  6. Bone Fracture Healing

  7. Biochemical Bone Fracture Healing Process Model Model Reference Control Architecture Multiple Source Derived QVC Behavior Biochemical Model Plant Architecture Biochemical Model Simulation Outputs

  8. Digestive System • Developed as part of modeling the bone fracture healing process • Specifically as part of a bone mineral regulation model • Uses only human organism information from open literature • Two models are developed • Daily and minute update interval rates • Focus on the calcium intake-absorption-1,25 dihydroxyvitamin D3 axes

  9. Digestive System Dietary Input Serum Input Meal Processor #1 Meal Processor #2 Meal Processor #n … … Calcium Excretion Accumulator Calcium Absorption Accumulator Net Calcium Excretion Net Calcium Absorption

  10. Digestive System Dietary Input Serum Input Meal Processor #N Model Reference: Amount of Calcium Input Ca_In_T Fuzzify VD3_In Fuzzify Ca_In_T Defuzzify Fuzzy Rule Base CaP Fuzzy Asso Mem Ca_In Defuzzify Ca_In Fuzzify Ca_In Controller Plant Ca_Proc_T Calcium Absorption (t) Calcium Excretion (t)

  11. Behaviors

  12. Behaviors

  13. Behaviors Bioelectrical Component Model Reference Adaptive Control System Structure of the Bone Fracture Healing/Remodeling/Regeneration Process Model/Simulation Stimulation Assessment, and Tibia Cooperative/ Goal Coordinator Stimulation Stimulation and Goal Management Inputs Response and Status Outputs ref_BEP ref_BEP Reference Adaptation Adapt QVC, Strain Rate + Controller Plant BEP ΔBEP ΔQVC –

More Related