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Modeling of sub-cellular processes

Modeling of sub-cellular processes. Muscle contraction is caused by release of calcium from intracellular compartments We study different triggers for this release The model includes diffusion of calcium and sodium ions and transport of these ions through cell membranes

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Modeling of sub-cellular processes

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  1. Modeling of sub-cellular processes • Muscle contraction is caused by release of calcium from intracellular compartments • We study different triggers for this release • The model includes diffusion of calcium and sodium ions and transport of these ions through cell membranes • Co-work with Institute for Experimental Medical Research at Ullevål University Hospital

  2. Co-operation of membrane channels

  3. Matematical Formulation, sodium A diffusion equation governs intracellular sodium (s). Membrane currents are incorporated as boundary conditions.

  4. Matematical Formulation, calcium The diffusion of calcium (c) is more complicated due to different types of intracellular buffers.

  5. Calcium induced Calcium release

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