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. . ??????????????????????? ??????????????????????????????????????????? ???????????????????????????????????. ELECTRODIAGNOSIS ??????? . . . . Basic Physiology of Nerve TissueResting membrane potentialAction Potential.
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1. Woraphon Aramrussameekul, MD
2. ???????????????????????
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3.
Basic Physiology of Nerve Tissue
Resting membrane potential
Action Potential
14. Relative C/I Bleeding tendency: Aspirin, anticoagulant
Skin infection of dermatitis
Region of vital organs
17. COMPONENTS AND SHAPE OF THE SNAP Latency (msec) ;
- Initial Latency ( conduction time)
- Peak Latency
Amplitude (uv)
Nerve conduction velocity
(m/sec)
NCV.= DISTANCE / LATENCY
18. SNAP DIFFERENTIATION BETWEEN ORTHODROMIC AND ANTIDROMIC STIMULATION Orthodromic Response Antidromic Response
SNAP AMPLITUDE smaller bigger
SNAP SHAPE unipolar bipolar
CONDUCTION TIME same same
( LATENCY )
NCV. same same
20. 1. Prolonged distal latency ;
low temperature
generalized/ focal/ multifocal demyelination
2. Slow conduction velocity ;
diffuse demyelination
loss of large myelinated fibers
focal / multifocal demyelination
severe axonal stenosis
3. Decrease amplitude ;
temporal dispersion
conduction block
loss of axonal nerve fibers severe axonal stenosis
21. MOTOR NERVE CONDUCTION STUDY
24. STIMULATION - Supramaximal intensity
PICK UP ;
Active electrode – motor point of muscle
Reference electrode - silence area
RECORD
; Compound muscle action potential
( CMAP / ‘ M ’ WAVE RESPONSE )
25. COMPONENTS AND SHAPE OF THE CMAP Latency (msec)
Amplitude (mv)
Conduction time
(msec)
Nerve conduction velocity(m/sec)
NCV.= D2-D1/L2-L1
29. ??????????????????????????????????????????
32. H REFLEX Stim.Tibial N.at popliteal fossa
Submaximal intensity
Record act.potential at medial gastrocnemius m. Monosynaptic Reflex
Stim.Ia afferent in m. spindle
Dorsal horn cell in spinal cord
Synapse with ant. horn c. (S1)
Deporalization ???? Act.Potential
35. Stim. motor fiber with supramaximal intensity
ventral root ,anterior horn cell
motor fibers,action potential
PROLONGED F WAVE CONDUCTION DEFECT IN
CENTRAL / PROXIMAL PATHWAY
F WAVE
37. Late response
H-reflex & F-wave
Study proximal region
Repetitive stimulation
Myasthenia gravis
Myasthenic syndrome of Lambert Eton
40. Needle electromyography: Interpretation includes analysis of oscilloscope tracings & characteristic sounds produced by electrical potentials
1. Insertional activity
2. Spontaneous activity
3. Motor unit action potential( MUAP)
4. Motor unit recruitment pattern
41. Abnormal findings in EMG Axonal involvement?
Neuropathy or Myopathy?
42. EMG IN NORMAL SUBJECT 1. Muscle at rest ??????????????????
- Insertional activity
- End-plate noise ; nerve potentials
miniature end plate potential
2. At minimal contraction
- Single motor unit action potential
3. At maximal contraction
- Complete interference pattern
43. EMG IN NORMAL SUBJECT
44. ??????????????????????????????????????
45. Spontaneous potential of single muscle fiber
sound Rain on tin roof
Regular rhythm ,
amplitude 50 - 300uv ,
duration 0.5 - 2 msec.
Diphasic / triphasic with initial phase positive
??????????? membrane irritability FIBRILLATION POTENTIAL
47. POSITIVE SHARP WAVE POTENTIAL Spontaneous potential
?????????? sharp positive deflection ??????? long duration negative phase of low amplitude
Sound Dull thud
?????? ??? ???????????????
??????????? membrane irritability
????????? fibrillation
49. EDx in orthopedics Nerve injury
Nerve entrapment
Nerve root compression or radiculopathy
BPI
Etc.
51. * The electrodiagnosis (EDX) is most helpful to patients with problems of weakness, paresthesia,pain or fatique.
* These can usually be diagnosed with respect to anatomical localization, severity, and nature of dysfunction.
* Electrodiagnosis can support or confirm clinical diagnosis and have an important role in prognosis and guiding management of a variety of neuromuscular conditions.
52. CONCLUSION EDX : adjunct investigation to the Hx, P.E. & other Investigations to provide the definite diagnosis
EDX : LMN lesion
54. Summary Root : 3 Dorsal scapular C5, nerve to subclavius, Long thoracic n.C5-7
Trunk : 1 Suprascapular n. C5-6
Division
Cord : 3 5 5
Branch
55. Root : Dorsal scapular N. C5
56. Cord Lateral cord : 3
Lateral pectoral n.
Musculocutaneous n.
Median n.
Medial cord : 5
Medial pectoral n.
Medial cutaneous n. of arm
Medial cutaneous n. of forearm
Ulnar n.
Median n.
Posterior cord : 5
Radial n.
Axillary n. : Deltoid Teres minor
Thoracodorsal n. : Latissimus dorsi
Upper subscapularis n.
Lower subscapularis n.
57.
58. Thigh muscles
59. Leg muscles