Grant Writing Introduction

1. Grant Writing Introduction Overview of Grantwriting NIH

2. Grant Writing IntroductionOverview Why Seek Funding? Some of the many reasons include: Enables your research and professional standing Attracts high quality Ph.D. students (you can hire them as RAs) Gives you more time for research (or more money for doing research Enables course releases Enables focus in summer on research instead of teaching Enables interdisciplinary (and other) collaborations (you can pay other people to work on the project). Gives you the funds to pay for research couldn’t otherwise do. Often viewed as a measure of quality research by Deans and others. Helps your school (overhead, reputation) Enhances the reputation of the broader profession

3. What are Potential Sources of Funding? Foundations/Corporate Sources of Funds+ Internal University Resources Overall possibilities: http://www.infoed.org/new_spin/spinmain.asp Foundations http://foundationcenter.org/findfunders/http://foundationcenter.org/pnd/rfp/cat_education.jhtml;jsessionid=XMUBUJN4SKHEPTQRSI4CGW15AAAACI2F For example Spencer foundation- http://www.spencer.org/programs/grants/research_grants.htm http://www.agmconnect.org/RCP/guide1.htm Corporate http://foundationcenter.org/findfunders/topfunders/top50giving.html (top 50 corporate funders) http://www.ncte.org/about/grants/sources/107742.htm •Internal funds http://www/usc.edu/research/vice_provost/awards/zumberge.html

4. Do you have a Commercialization Partner? • Would the research you’d like to do be relevant to product development for commercialization? a marketing strategy? Validating the effectiveness of a product? Then the following might be a good way to go (especially if you have a corporate, experienced grant-getting partner): • SBIR (Small Business Innovation Research) Award Mechanisms • STTR (Small Business Technology Transfer) Award Mechanisms

5. State Agencies (California) http://www.ucop.edu/srphome/ • University Aids Research Program • http://uarp.ucop.edu/ • California Breast Cancer Research Program • http://www.cbcrp.org/research/

6. Sources of Federal Government Funding http://www.grants.gov/ http://www.fedbizopps.gov/http://www.bnl.gov/techxfer/wfo/wfo_federal.asp National Science Foundation http://www.nsf.gov Dept. of Health and Human Resources NIH http://www.nih.gov Office of Minority Health http://www.cdc.gov/omh Substance Abuse & Mental Health Services Adm. http://www/samhsa.gov/index.aspx CDC http://www.cdc.gov Administration on Aging http://www.aoa.gov/

7. Sources of Federal Government Funding Defense Grants http://www.acq.osd.mil/ddre/research/ DTRA http://www.dtra.mil/ DARPA http://www.darpa.mil/ AFRL(AFOSR) http://www.afosr.af.mil/ ARO http://www.arl.army.mil/main/main/default.cfm?Action=29&Page=29 ONR http://www.onr.navy.mil/default.asp Department of Education http://www.ed.gov/index.jhtml http://www.ed.gov/fund/grant/apply/grantapps/index.html

8. Grant Funding What’s the Match? What are you bringing to the table? What do they want? How can you tell?

9. You What’s your 5-year strategic plan for your career? How does this project fit into it? resources, expertise, skills have or could leverage, build? Funder Who funds projects relevant to your goals? What’s the match between your goals and agencies goals/mission/ funding priorities, constraints, cost/benefit analysis? Do they provide awarded grant abstracts to check on the match? What’s the Match?

10. NIH •NIH: Funding Agency Focus •Background on NIH

11. How Are The NIH Institutes Organized? Director IntramuralDirector Extramural Director Intramural Program Extramural Program Research Laboratories on NIH Campus and Elsewhere Divisions/Centers/ Branches (Managing External Funding)

12. How Is The NIH Organized? NIH Extramural Funding Components

13. NIH: Funding Agency Focus Which Agency will review your proposal? This could impact your funding success. Start with an overall description of each located here: http://www.nih.gov/icd/

14. Click on the link to the Center for Scientific Review • http://cms.csr.nih.gov/ • Under “Peer Review Meetings” select • •Review group descriptions (check these out) • •Study Section Rosters (click link); Check these people out! • • Decide if there are any RFA (set asides), RFPs (conracts) • that might be relevant to your work you want to apply for, • these might be funded by specific agencies. • • Determine probability of funding via a given agency • http://grants1.nih.gov/grants/award/success.htm • • Check out grants funded by a given agency • http://crisp.cit.nih.gov/ Which Agency at NIH?

15. Success Rates by Institutes http://grants1.nih.gov/grants/award/success/Success_ByIC.cfm(2005)

16. Which Award Mechanism? If you don’t already have your Ph.D.: F31 Minority Supplement (Must be African American, Hispanic, Native American, Alaskan Native, or Pacific Islander) or Supplement for disabled students. F30 Individual Predoctoral Awards (Must be enrolled in MD/Ph.D. program) F31 Predoctoral Fellowship Awards (Must have completed qualifying exams; for dissertation research/training) Training Grants (faculty have to submit these but you could work on these with them)

17. Which Award Mechanism? If you have your Ph.D. and need more mentoring (new investigator- no prior NIH funding orange awards): K01 Mentored Research Scientist Development Award (3-5 years of additional supervised research) K25 Mentored Quantitative Research Career Development Award (if switching to biomedical field with background in statistics/math; previous background not focused on disease).•F32 Individual Postdoctoral Fellowship (in similar field) Don’t need 3-5 years additional supervised research experience (but haven’t competed successfully for funding yet): K22: Career Transition Award K23: Mentored Patient-Oriented Research Career Development Award (need clinical doctoral degree or equivalent)•K08: Mentored Clinical Scientist Development Award (Clinical Doctoral Degree) K24 Midcareer investigator award in Patient oriented researc•K26 Midcareer investigator award in Mouse Pathobiology Research RO3: Small Grant (not much preliminary data) R01: Traditional Research Grants (note new investigator status if you are one) R15: Area grants (restricted by institutional NIH activity) R21: Exploratory/Developmental Research Grant (up to 275K; 2 years)

18. Agency Review Criteria (NIH) Significance Approach Innovation Investigators Environment Other

19. Significance (also see Gerin, W. (2006). Writing the NIH Grant Proposal: A Step-by-Step Guide . Thousand Oaks, CA: Sage Publications; buy this book if you are thinking about writing an NIH grant-- very helpful!) Does the study address an important problem? If the aims of the application are achieved, how will scientific knowledge or clinical practice be advanced? What will be the effect of these studies on the concepts, methods, technologies, treatments, services, or preventative interventions that drive this field?

20. Approach Are the conceptual or clinical framework, design, methods, and analyses adequately developed, well integrated, well reasoned, and appropriate to the aims of the project? Does the applicant acknowledge potential problem areas and consider alternative tactics?

21. Innovation Is the project original and innovative? For example, does the project challenge existing paradigms or clinical practice? Does it address an innovative hypothesis or critical barrier to progress in the field? Does the project develop or employ novel concepts, approaches, methodologies, tools, or technologies for this area?

22. Investigators Are the investigators appropriately trained and well suited to carry out this work? Is the work proposed appropriate to the experience level of the principal investigator (PI) and other researchers? Does the investigative team bring complementary and integrated expertise to the project?

23. Environment Does the scientific environment in which the work will be done contribute to the probability of success? Do the proposed studies benefit from unique features of the scientific environment, or subject populations, or employ useful collaborative arrangements? Is there evidence of institutional support?

24. Other Protection of Human Subjects Inclusion of Women, Minorities, and Children Care and Use of Vertebrate Animals Budget Foreign applications

25. First Step in Writing a New Grant