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Insulin Resistance and PCOS

Conclusions. Increasing evidence that PCOS is associated with insulin resistanceData seems to suggest differences between IR associated with obesity and IR associated with PCOSData also notes peripheral IR and maintenance of ovarian insulin sensitivity. Conclusions. Obese and lean PCOS phenotypes

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Insulin Resistance and PCOS

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    1. Insulin Resistance and PCOS

    2. Conclusions Increasing evidence that PCOS is associated with insulin resistance Data seems to suggest differences between IR associated with obesity and IR associated with PCOS Data also notes peripheral IR and maintenance of ovarian insulin sensitivity

    3. Conclusions Obese and lean PCOS phenotypes Ovarian androgen dysregulation may be a primary pathogenetic mechanism Serine phosphorylation may link post- receptor insulin resistance and selective uncoupling of ovarian thecal androgen biosynthesis

    4. Conclusions Implications for PCOS-insulin resistance cardiovascular risk, conversion to glucose intolerance Associated with oligomenorrhea Metabolic syndrome profile Obesity is augmentative

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