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Differential Diagnoses: Could it be a pesticide?. Pesticide Health Effects Medical Education Database (PHEMED). The Great Decievers. Syphilis Lupus AIDS Pesticide Poisonings. S. Holland ‘07. Sometimes Easy-Sometimes Hard. General Bad Feeling
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Differential Diagnoses:Could it be a pesticide? Pesticide Health Effects Medical Education Database (PHEMED)
The Great Decievers • Syphilis • Lupus • AIDS • Pesticide Poisonings
S. Holland ‘07 Sometimes Easy-Sometimes Hard • General Bad Feeling • Nausea, weakness, fatigue, lightheadedness, headache, nausea • Differential Diagnosis • Viral illness • Early onset diabetes • Incipient malaria • Dehydration • Pesticide poisonings
(Semi) Unique Signs-Symptoms • Miosis: cholinesterase inhibitors • Mydriasis: cyanide/flouride • Acral and perioral parasthesias: pyrethroids • Yellow skin color: nitrophenols • Hair loss: thallium • Peripheral Neuropathy: arsenic & OP’s • Methemoglobinemia (blue baby): sodium chlorate, creosote • Skin burn: paraquat
Seizures Organochlorine insecticides may cause isolated grand mal seizures Late stage organophosphates Fipronil Metabolic Acidosis Boric Acid ingestion (scalded baby syndrome) Herbicides (glyphosate) Cardiac Arrythmias Organophosphates and Torsade de pontes and bradycardia Other Manifestations • Bloody diarrhea • arsenic-thallium • Pulmonary edema • organophosphates and carbamates • Altered mental status • Several pesticides • Hypermetabolism • Dinoseb • Pentachlorophenol
Manifest in Multiple Systems • Nervous – central & peripheral • Cardio-vascular • Gastrointestinal & Hepatic • Skin • Eye • Hematopoietic • Respiratory • Renal