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Learn about anorexia nervosa and bulimia nervosa, their subtypes, risk factors, statistical data, complications, and laboratory abnormalities. Discover psychological, biological, family, and sociocultural influences on eating disorders.
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Anorexia Nervosa (AN) • Refusal to maintain 85% of ideal body weight • Intense fear of gaining weight or becoming fat • Disturbed perception of the shape or size of the body • Denial of the seriousness of the problem • Amenorrhea—3 months without period
Subtypes of AN • Restricting • Lose weight primarily through dieting, fasting, or excessive exercise • Binge-eating/Purging • Person regularly engages in binge eating or purging • Purging is self-induced vomiting, misuse of laxatives, diuretics, or enemas
Bulimia Nerovsa (BN) • Recurrent episodes of binge eating (eating a large amount of food given the context with an associated sense of loss of control) • Recurrent inappropriate compensatory behavior (purging, fasting, excessive, exercise) • Binge eating and compensatory behavior occur at least 2 times per week • Clients are usually normal body weight or overweight
Subtypes of BN • Purging type • Person regularly engages in self-induced vomiting or the misuse of laxatives, diuretics, or enemas • Non-purging type • Person regularly engages in other inappropriate compensatory behavior—fasting or excessive exercise
Who’s at Risk for AN and BN? • Adolescents • Athletes • Appearance focused professionals
Demographic Factors • Females comprise 95% of those with EDs • Onset of AN ranges from pre-puberty to the 30s, but generally occurs between 12-18 • Onset of BN typically begins during late adolescence or early adulthood
Statistical Data • 10-18% mortality rate • Highest mortality rate of any of the psychiatric disorders • Death most frequently occurs by starvation, electrolyte disturbances, or suicide • People who have had the disease greater than 20 years have a 20-25% increased mortality rate • Long term data—no more than 50% recover completely
Statistical Data (cont) • Prevalence rates of 0.5-1% among females in late adolescence and early adulthood who meet full criteria for AN • 1-3% with BN
Psychological Factors • Low self-esteem • Perfectionism and unrealistically high standards • Difficulties in self-soothing and mood modulation
Biological Factors • 8 times the risk if family member has ED • 50% concordance in monozygotic twins, 15% for dizygotic • A family history of mood or anxiety disorders or OCD increases the risk of EDs
Biological Factors • Many neurochemical changes occur with EDs • Low NE levels are seen in clients during periods of restricted intake • High levels of 5-HT and its precursor tryptophan have been linked to satiety • Low levels of 5-HT have been found in clients with BN and the binge-purge subtype of AN
Family Factors • AN • Family is rigid about values and rules • Overprotective • Unable to deal with conflict • BN • Family is chaotic with loose boundaries • Perceived as less caring • Unrealistic expectations for achievement • Parental concerns with weight
Sociocultural Factors • Cultural ideal of being thin • Media focus on beauty, thinness, and fitness • Chronic dieting, particularly among young women
Comorbid Illnesses • AN • Depression • Dysthymia • OCD/OCPD • Anxiety Disorders • Avoidant PD
Comorbid Illnesses • BN • Depression • Dysthymia • Substance abuse • BAD • BPD • Avoidant PD
Dermatologic Complications • Dry skin • Lanugo-like hair • Alopecia • Brittle nails • Pale skin • Cyanosis
Cardiac Complications • Low heat rate—30-40s common • Low BP • Decrease in heart size • CHF—biggest risk factor for death • MI • Arrhythmias • Death
Respiratory Complications • Decrease in the number of breaths per minute • Decrease in respiratory muscle tone
Gastrointestinal Complications • Delayed gastric emptying • Bloating • Constipation • Abdominal pain • Gas • Diarrhea
Musculoskeletal Complications • Loss of muscle mass • Loss of fat • Osteoporosis • Pathologic fractures
Hematologic Complications • Leukopenia • Anemia • Thrombocytopenia • Hypercholesterolemia • Hypercarotonemia
Neuropsychiatric Complications • Abnormal taste sensation • Apathetic depression • Mild organic mental sx • Sleep disturbances
Metabolic Complications • Electrolyte abnormalities • Particularly hypokalemia and hypomagnesemia • Elevated BUN
GI Complications • Salivary gland enlargement • Pancreatic inflammation with elevated serum amylase • Esophageal irritation • Gastric erosion
Dental Complications • Erosion of dental enamel
Neuropsychiatric Complications • Seizures • Mild neuropathies • Fatigue • Weakness • Mild organic mental sx
Labs • Routine labs include: • CBC • Electrolytes • Serum glucose levels
Labs (cont) • RBCs—low • Hgb and Hct elevated due to hemoconcentration • WBCs—low • Na, K, Cl—low in purging, diuretic, or laxative use • Serum glucose—low
Rx • Cognitive behavioral therapy • Pharmacologic therapy
CBT • Use strategies designed to change the client’s thinking (cognition) and actions (behaviors) about food • Focus on: • Interrupting the cycle of dieting, binging, and purging • Altering dysfunctional thoughts and beliefs about food, weight, and body image
Pharmacology • SSRIs have shown success with weight maintenance and treatment resistant AN • Prozac and Celexa • Zyprexa—being researched to treat low weight and rx resistant individuals with high levels of anxiety • May need meds to treat co-morbid illness • WB--contraindicated
Refeeding • Calorie calculation • 25-35 kcl x current weight • Increase calories by 200-300 kcl every 2-3 days (1-2 lb gain/week) • Fluid intake of at least 1500cc/day • Daily weights
Refeeding Syndrome • Greatest risk of cardiac complication is within the 1st two weeks of refeeding • The myocardium is less able to withstand the stress of increased metabolic demands because left ventricular mass and contractility have been reduced • Hypophosphatemia—causes decreased cardiac stroke volume • Electrolyte abnormalities
Recovery • Long-term study of AN • 50% fully recovered • 25% had intermediate outcomes • 10% still met criteria for AN • 15% had died of causes r/t AN • Best indicator for recovery is return of menses
Recovery • 50 % recover fully • 20% continue to meet criteria for BN • 30% have episodic bouts • Death rate with BN is estimated to be 0-3%