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Wu, Kuan-Yi. Properties of minD/ ParA superfamily. Structurally similar ATPase activity Polymerization Other playes dynamic oscillation. (ParA). The relationship between players. Placement of division sites C: inhibitor of septation D: membrane recruitment of C
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Properties of minD/ ParA superfamily • Structurally similar • ATPase activity • Polymerization • Other playes • dynamic oscillation (ParA)
The relationship between players Placement of division sites • C: inhibitor of septation • D: membrane recruitment of C • E: topological specificity DNA partition • A: recruited by B • B: recognize parS • S: cis-element in arrays YFP-MinD/ MinE-CFP
1 ADP MinD MinD - - - + + + 5 P MinC MinE 2 MinE 3 ATP ATP ATP ATP MinC MinE 4 MinC ATP ATP MinD MinD MinD MinD MinD Molecular mechanism of the oscillating Min system C-terminus