Stem Cell Treatment for Rheumatoid Arthritis

1. Stem Cell Treatment for Rheumatoid Arthritis • One of the mostpainful and crippling disease is Rheumatoid arthritis (RA). By nature, it is an auto-immune disease and affects multiple systems of the body and therefore called a systemic disease which primarily attacks the joints. Auto immune disorders are those orders in which the protecting cells mistakenly start attacking the body’s own tissues. • Most probably, this type of immune system attacks the joints initially and then the surrounding tissues. Gradually it progresses and attacks other organs of the body as well. These cells continue to grow in the body till the person or animal is alive. It may be turned into other particular cells that provide healthy growing cells free of the disease and can be used for treatment of many disorders, including Rheumatoid arthritis. • At present, RA is treated with immune restrictive agents such as steroid hormones, methotrexate, cyclosporine, gold, and the most recent treatment of infliximab (Remicade). In spite of bringing on short-term improvement, these advancements possess permanent and unpleasant effects due to imprecise prohibition of immune responses. Moreover, existing treatments do not cover the damage of tissues which has already attacked on joints or extra-articular tissues. • Stem cell preservationfor treatment, on the other hand, demonstrates to induce deep healing activities with various forms of arthritis. The utilization of adult stem cells treats the arthritis caused by patient’s own fat which has been called asautologous adipose tissue. • Treatment Procedure: The fat tissue is accumulated by mini-liposuction. This accumulation is performed by a certified plastic surgeon under a state of total unconsciousness resulting from anesthetic drugs. T regulatory cells and Mesenchymal stem cells are found within this tissue and further separate the somatic cells from the fat. The whole process is submitted to severe quality control and before they are permitted to treatment, the enduring fatty stem cells are tested for quality, bacterial contagion and endotoxin. • Besides the treatment of damaged tissues, stem cell preservation have the distinctive ability to transform the immune system to block off morbid responses. The other stem cells and specially the mesenchymal stem cells home to swollen tissues and give rise to instigative agents. But these mediators proceeds only in the local areas and do not inhibit the immune reaction of the entire body. In addition, stem cells of mesenchymal persuade the yielding of T regulatory cells, which is a kind of resistant cell and protects the body against immunological attack by itself.