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Rheumatoid arthritis

Rheumatoid arthritis. Tena Trbojević Mentor: A. Žmegač Horvat. Rheumatoid arthritis. chronic diesease inflammatory disease (inflammation of joint lining ) autoimmune disease

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Rheumatoid arthritis

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  1. Rheumatoid arthritis Tena Trbojević Mentor: A. Žmegač Horvat

  2. Rheumatoid arthritis • chronic diesease • inflammatory disease (inflammation of joint lining) • autoimmune disease (immune reaction against joint tissues - synovial membrane)

  3. Rheumatoid arthritis • causes pain, swelling, stiffness, loss of function in the joints • generally occurs in a symmetrical pattern • may also attack tissue in the skin, lungs, eyes, and blood vessels

  4. Rheumatoid arthritis • small joints of hands and feet affected first, larger joints later

  5. Rheumatoid arthritis • begins during the most productive years(30 – 60) • occurs much more frequently in women than in men (w:m=3:1)

  6. Rheumatoid arthritis • specific agent or agents are not yet known • infectious agents, such as viruses and bacteria, may trigger RA in people with an inherited tendency to develop the disease

  7. Rheumatoid arthritis • synovitis • fibrous ankylosis • bony ankylosis • osteoporosis

  8. Rheumatoid arthritis

  9. Rheumatoid arthritis - symptoms: Around the joints • warmth • redness • swelling • pain • limitations in joint motion General • sickness • tiredness • fever

  10. Rheumatoid arthritis • can be difficult to diagnose in its early stages • Patient history - questions about the intensity of pain symptoms - frequency of symptoms - what makes the pain better or worse • RTG, MRI, arthrography, arthroscopy • Blood test (RF, CRP, SE) RF→ Waaler- Rose test 1:32=normal 1:64≤ pathological

  11. Rheumatoid arthritis Treatments can: • relieve pain • reduce swelling • slow down or help prevent joint damage • increase ability to function • improve sense of well-being

  12. Rheumatoid arthritis – treatment options: • exercise • medication • stressreduction • DMARDs (disease-modifying anti-rheumatic drugs): methotrexate, leflunomide, sulfasalazine, cyclosporine • corticosteroids : cortisone, hydrocortisone, prednisone • in some cases - surgery (joint replacement and tendon reconstruction - two types of surgery available to patients with severe joint damage )

  13. Rheumatoid arthritis • research efforts: focused on developing drugs that can reduce inflammation and slow or stop the disease with few side effects; investigators trying to identify the infectious agents and understand how they work → new therapies • scientists are also examining why rheumatoidarthritis often improves during pregnancy

  14. Rheumatoid arthritis • http://www.medicinenet.com/rheumatoid_arthritis_pictures_slideshow/article.htm • http://video.about.com/arthritis/Chronic-Rheumatism-Hand.htm • http://nihseniorhealth.gov/videolist.html#rheumatoidarthritis

  15. References: http://nihseniorhealth.gov/videolist.html#rheumatoidarthritis http://www.medicinenet.com/rheumatoid_arthritis_pictures_slideshow/article.htm http://video.about.com/arthritis/Chronic-Rheumatism-Hand.htm

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