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Borrelia burgdorferi

Borrelia burgdorferi. By: Matt Hryniewicki. Classification. Domain: Bacteria Kingdom: Bacteria Phylum: Spirochaetes Order: Spirochaetales Family: Spirochaetaceae Genus: Borrelia Species: B. burgdorferi. Structure. Helical Shape Contains inner and outer cell membrane

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Borrelia burgdorferi

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  1. Borreliaburgdorferi By: Matt Hryniewicki

  2. Classification • Domain: Bacteria • Kingdom: Bacteria • Phylum: Spirochaetes • Order: Spirochaetales • Family: Spirochaetaceae • Genus: Borrelia • Species: B. burgdorferi

  3. Structure • Helical Shape • Contains inner and outer cell membrane • Flexible cell wall • The cell’s flagella are located inside the periplasm between the inner and outer cell membranes (endoflagella) • Allows cell to travel through highly viscous fluids and materials • Highly invasive • Outer surface proteins • Can turn into a cyst if in unfavorable conditions • Converts back to spirochete under favorable conditions

  4. Metabolism • Relies on host for energy precursors • Limited metabolic capabilities • Contains many transport proteins that are used to obtain compounds from host serum or environment • Uses carbohydrates as source of energy in mammals • Uses N-acetylglucosamine as a major source of energy in ticks. • Produces ATP solely by using substrate-level phophorylation

  5. Nutrition • Can be cultivated in vitro • Growth medium contains over 13 ingredients in a rabbit serum base • Optimal temperature is 32 degrees Celsius • Microaerophile or anaerobic

  6. Gram Stain • Negative gram stain

  7. History • First recorded in 1883 by Alfred Buchwald • Discovered in 1982 by Dr. Willy Burgdorfer • Several cases popped up in the towns of Lyme and Old Lyme in 1975

  8. Disease Causing • Causes Lyme Disease • Carried by ticks • Ticks pick up the bacteria from infected mice and deer • Produces a “bulls-eye” rash • Treated with antibiotics if predicted within 72 hours • Ibuprofen used to relieve joint stiffness • Most prevalent tick-borne illness in the U.S.

  9. Works Cited • Abedon, Stephen T. "Bacteria Binomials." Ohio State Mansfield. 26 Apr. 1998. Web. 03 Feb. 2011. <http://mansfield.osu.edu/~sabedon/biol4045.htm>. • "BorreliaBurgdorferi - MicrobeWiki." MicrobeWiki - MicrobeWiki. Ed. Dan Holligan. Web. 03 Feb. 2011. <http://microbewiki.kenyon.edu/index.php?title=Borrelia_burgdorferi& redirect=no>. • "BorreliaBurgdorferi." RIT - People - Home. Web. 03 Feb. 2011. <http://people.rit.edu/mrppph/animals/pages/borrelia burgdorferi.htm>. • "Classification." BioWeb Home. Web. 03 Feb. 2011. <http://bioweb.uwlax.edu/bio203/s2007/joyce_kait/classification.htm>. • "Disease Carriers." Wadsworth Center. New York State Department of Health. Web. 3 Feb. 2011. • "Influenza." Medical Ecology @ Www.MedicalEcology.org. Web. 03 Feb. 2011. <http://www.medicalecology.org/diseases/lyme/lyme_disease.htm>.

  10. "Lyme Disease Crash Course--Everything You Need to Know in 5 Mins. | Facebook." Welcome to Facebook - Log In, Sign Up or Learn More. Web. 03 Feb. 2011. <http://www.facebook.com/note.php?note_id=25754076527>. • "Lyme Disease." Our Politics: Changing the Way Politics Works One Blog Post at a Time. | Just Another WordPress Site. Web. 03 Feb. 2011. <http://www.ourpoliticsblog.com/huhu/lyme-disease.html>. • "Lyme Disease." Wikipedia, the Free Encyclopedia. Web. 03 Feb. 2011. <http://en.wikipedia.org/wiki/Lyme_disease>. • "Microbial Spore Formation." MicrobeWorld. 14 Jan. 2009. Web. 03 Feb. 2011. <http://www.microbeworld.org/index.php?option=com_content&view= article&id=160&Itemid=84>. • Newsfox - Daily News and Press Releases. Web. 03 Feb. 2011. <http://www.newsfox.com/show_attach.mc?pte=080930034>. • "PubMed Health - Lyme Disease." NCBI. 23 Feb. 2010. Web. 03 Feb. 2011. <http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0002296>. • Todar, Kenneth. "Lyme Disease." Online Textbook of Bacteriology. 2011. Web. 03 Feb. 2011. <http://www.textbookofbacteriology.net/Lyme.html>. • "Viewing the Arrangement of BorreliaBurgdorferi Flagella by Electron Cryotomography." Spirochetes Unwound. Web. 03 Feb. 2011. <http://spirochetesunwound.blogspot.com/2009/02/viewing- arrangement-of-borrelia.html>. • Web. 03 Feb. 2011. <http://www.ncbi.nlm.nih.gov/pubmed/12422604>.

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