1 / 11

Predicting the Chronic Effects of PAHs using the Target Lipid Model of Narcotic Toxicity

Explore chronic effects of PAHs using the Target Lipid Model of Narcotic Toxicity, predicting impact on growth, reproduction, and mortality. Learn about QSARs, concentration computations, and HC5 values for water and sediment. Presented at SETAC North America 27th Annual Meeting.

jsackett
Download Presentation

Predicting the Chronic Effects of PAHs using the Target Lipid Model of Narcotic Toxicity

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Predicting the Chronic Effects of PAHs using the Target Lipid Model of Narcotic Toxicity Joy McGrath Dominic Di Toro HydroQual, Inc. SETAC North America 27th Annual Meeting Montreal, Canada November 5-9, 2006

  2. Acknowledgement Funding for this project was provided by the Coastal Response Research Center www.crrc.unh.edu

  3. Acute Toxicity QSARs for Narcotics

  4. Computation of Effect Concentrations

  5. Acute Effects (lethality) – Single Exposures Water Column Sediment

  6. Chronic Effects (Growth, Reproduction, Mortality) – Single Exposures

  7. Water Column – Chronic Sublethal Effects

  8. 90% Confidence Limits in Predicted Effect Concentration

  9. Water Column – Other Chronic Sublethal Effects - PAH Mixtures Rhodes et al, 2005

  10. HC5 Values for Water and Sediment

  11. Comparison of HC5s and NOECs for PAHs WATER SEDIMENT

More Related