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Schizophrenia Jeopardy: Diagnosis, Course, and Treatment

Test your knowledge of schizophrenia with this Jeopardy game. Explore topics such as diagnosis, course of illness, and treatment options for this mental disorder.

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Schizophrenia Jeopardy: Diagnosis, Course, and Treatment

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  1. Jeopardy for the Psychiatry Clerkship

  2. And Now Here Is The Host . . . is proud to present Insert Name Here

  3. The categories for today’s Jeopardy on Schizophrenia will be:

  4. Diagnosis

  5. Course of Illness

  6. Treatment

  7. 1st GenerationAntipsychotics

  8. 2nd Generation Antipsychotics

  9. Diagnosis 2nd Gen AP’s Course of Illness Treatment 1st Gen AP’s 100 100 100 100 100 200 200 200 200 200 300 300 300 300 300 400 400 400 400 400 500 500 500 500 500 600 600 600 600 600 700 700 700 700 700 800 800 800 800 800 900 900 900 900 900

  10. Row 1, Col 1 What are negative symptoms? (alogia, affective flattening, avolution, anhedonia) Males are more likely than females to have these A Criteria symptoms of schizophrenia

  11. 1,2 What are hallucinations? Positive symptoms of schizophrenia are delusions, disorganized thinking, and this

  12. 1,3 What is schizophreniform disorder? If the A criteria for Schizophrenia have been met for between 1 & 6 months, the diagnosis is this

  13. 1,4 What are mood disorders? Before diagnosing schizophrenia, exclusionary diagnoses that must be ruled out include: other psychotic disorders, childhood developmental disorders, medical or neurological illness, substance abuse or medication induced, personality disorders, & this

  14. 1,5 What is tact (social cognition)? Regarding the cognitive symptoms of schizophrenia, the mnemonic SMART refers to speed, memory, attention, reasoning, and this

  15. 1,6 What is anhedonia? This A criteria negative symptom of schizophrenia is also a symptom of major depression

  16. 1,7 What is disorganized thinking/speech? To meet DSM5’s A criteria of Schizophrenia, of the 2 symptoms 1 needs to be a delusion, a hallucination, or this

  17. 1,8 What is catatonia? Seen in schizophrenia & other disorders, stupor, waxy flexibility, mutism, negativism, stereotypy, & echolalia, are motor activities that are seen in a patient with this

  18. 1,9 What are hypnopompic hallucinations? Voices that are only heard when a patient is just waking up from sleeping are called this

  19. 2,1 What are negative symptoms (or cognitive symptoms)? These symptoms of schizophrenia present early in the illness, worsen during the active periods, & do not respond well to anti-psychotic medications

  20. 2,2 What is get married? It is “proposed” that because most patients with schizophrenia have limited social contacts, only 30-40% do this

  21. 2,3 What is 10%? (~30% intermittent course, ~60% chronic course) 10%, 30%, 60%: the percentage of patients with schizophrenia who experience a single active episode is this

  22. 2,4 What is a prodrome? Seen in ~85% of patients prior to the 1st psychotic episode, this negative prognostic sign lasts several months to years

  23. 2,5 What is a 2nd smaller peak age of onset peak for females after age 40? For ♂ &♀ with schizophrenia, the peak age of onset (the mode) is the same but the average age of onset is different because of this

  24. 2,6 What is cardiovascular disease? Patients with schizophrenia have a life expectancy that is about 25 years less than the general population primarily due to this

  25. 2,7 What is theprodrome? The functional decline for a patient with schizophrenia begins during this phase of the illness

  26. 2,8 What is live independently? Due to their many problems as outlined in the B criteria, only 33% of those with schizophrenia are able to do this on July 4th

  27. 2,9 What is males generally develop the illness earlier? The average course of schizophrenia tends to be more severe in males than females because of this

  28. 3,1 What is prevent relapse into the active phase? For patients with schizophrenia, the main goal of continuous pharmacologic treatment with antipsychotics is this

  29. 3,2 What is increased risk of relapse? Decreasing the antipsychotic medication in an attempt to use the “lowest effective dose” is associated with this

  30. 3,3 What is psychosis/active phase of illness? The most common reason patients with schizophrenia are psychiatrically hospitalized is this

  31. 3,4 What is 2 weeks? Except for clozapine (Clozaril), all anti-psychotic medications are unlikely to work by 4 weeks if a patient does not show a response within this number of week(s)

  32. 3,5 What is greater sensitivity to medication side effects? Lower doses of antipsychotics are used to treat patients with the first active phase of schizophrenia because of this

  33. 3,6 What is decreases risk of suicide? Clozapine (Clozaril) for patients with schizophrenia and lithium for patients with bipolar disorder both have this same unique benefit

  34. 3,7 What is recurrent suicidality/violence? Common indications for a clozapine (clozaril) trial include: persistence of positive symptoms, failure of > 2 antipsychotic trials, co-morbid substance abuse, and this

  35. 3,8 What is 75-80% In treating patients with FGA’s, often titrating the dose up until side effects emerge corresponds to blocking this percentage of dopamine receptors

  36. 3,9 What is mesolimbic tract? In order to have the desired antipsychotic effect, medications need to block at least 65% of dopamine receptors in this pathway

  37. 4,1 What is anti-cholinergic activity (cholinergic blockade)? Low potency antipsychotics have common side effects of dry mouth, constipation, blurred vision, & urinary hesitancy due to this

  38. 4,2 What is dystonia? Young males may be at higher risk than the rest of the population for this EPS side effect of muscle spasms

  39. 4,3 What is remain static/unchanged (ongoing symptoms)? Improve, worsen, or remain unchanged: Once a patient develops tardive dyskinesia, the most common course of the symptoms is this

  40. 4,4 What is propranolol (indural) While amantadine (symmetrel), lorazepam (ativan), clonidine (catapres), even mirtazepine (remeron), can be used for treating akathisia, the first choice of medication for treatment is this

  41. 4,5 What is antihistiminic? The most commonly used adjunctive medications to treat EPS side effects are anticholinergic, dopaminergic, and/or this

  42. 4,6 What is low potency FGAs? chlorpromazine (thorazine) . While there is still a significant risk of EPS, patients are less likely to complain of EPS symptoms from this type of FGA

  43. 4,7 What is clozapine (clozaril)? About half of the patients with tardive dyskinesia show a 50% symptom reduction from treatment with this medication

  44. 4,8 What is older adults/geriatric (>70 y/o)? The risk of tardive dyskinesia in patients who take FGA’s for 24 months is 50% in this age group

  45. 4,9 What is akathisia? An EPS side effect often described as a subjective sense of restlessness (the person can’t sit still) is this

  46. 5,1 What is clozapine (clozaril) and quetiapine (seroquel)? These two SGA’s are least likely to have EPS side effects

  47. 5,2 What is aripiprazole (abilify)? This SGA has a particularly long half life and a low risk of metabolic syndrome, but is the SGA most likely to cause akathisia

  48. 5,3 What are risperidone (risperdal) & palliperidone (invega)? These 2 SGA’s are available in depot form but can cause dose dependent EPS & prolactin elevation

  49. 5,4 What isziprasidone (geodone)? This SGA has a low risk of metabolic syndrome, needs to be taken with food, and is the most likely SGA to cause qTc prolongation

  50. 5,5 What are olanzapine (zyprexa)? This SGA has the highest risk of metabolic syndrome, is very sedating, and the CATIE study showed patients are highly likely to be compliant

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