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Does R ibose can be the Fountain of Energy for Athletes?

Does R ibose can be the Fountain of Energy for Athletes?. Presented by Han Kyul Kim 2011. What is Ribose?. Definition & Characteristics - a five-carbon sugar - two different isotopes: D-ribose and L-ribose - a non-essential nutrient - a component of DNA, RNA, ATP, and riboflavin.

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Does R ibose can be the Fountain of Energy for Athletes?

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  1. Does Ribose can be the Fountain of Energy for Athletes? Presented by Han Kyul Kim 2011

  2. What is Ribose? • Definition & Characteristics - a five-carbon sugar - two different isotopes: D-ribose and L-ribose - a non-essential nutrient - a component of DNA, RNA, ATP, and riboflavin

  3. What is Ribose? • Supplemental forms - a powder, chewable tablet or capsule • Recommendation - 6―12 g/d marketed - 3―60 g/d studied • Governing body regulation - not a banned substance from NCAA, IOC, WADA and USADA

  4. Why is There an Interest in ribose? • Intense exercise - ↓ muscle energy stores • Restoration of energy stores - via de novo synthesis • D-ribose - the formation of PRPP - ↑ rate of nucleotides synthesis <The role of ribose in de novo synthesis of ATP> 5-Phosphoribosyl- 1-pyrophosphate

  5. Cycle ErgometerSprints • Hellsten et al. - 8 healthy male subjects - 15 x 10-second sprints twice per day for 7 days - 3 x 200 mg/kg body wt for 3 days: d-ribose vs. placebo - muscle biopsy from vastuslaterails

  6. Cycle ErgometerSprints • Hellsten et al. (cont.) Placebo Ribose

  7. Isokinetic Knee Extensions • Op’tEijnde et al. - 20 healthy male subjects - 15 x 12 maximal contractions twice per day - 4 x 4 g/kg for 6 days: ribose vs. placebo

  8. Conclusions • Ribose as an ergogenic aid (?) • Post-exercise recovery of ATP • Potential reasons - not an effective ergogenicagent - inadequate ribose does or ineffective dosing schedule - a different athletic activity needed

  9. Questions?

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