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SOCIAL PHARMACOLOGY RATIONAL DRUG USE. DR.Dr. Endang Isbandiati Soediono, MS, SpFK Dept.Pharmacology&Therapy,MedicalFaculty,AirlanggaUniversity Dept.Clinical Pharmacology,Dr.Soetomo-Teaching Hospital, SURABAYA. Rantai Pengobatan. Anamnesis Pemeriksaan Fisik Pemeriksaan Laboratorik
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SOCIAL PHARMACOLOGYRATIONAL DRUG USE DR.Dr. Endang Isbandiati Soediono, MS, SpFK Dept.Pharmacology&Therapy,MedicalFaculty,AirlanggaUniversity Dept.Clinical Pharmacology,Dr.Soetomo-Teaching Hospital, SURABAYA FKMSocPhaRatDruUseEIS09
Rantai Pengobatan • Anamnesis • Pemeriksaan Fisik • Pemeriksaan Laboratorik • Diagnosis/DD • Tindakan A. Regulasi/Nasihat B. Medik/Farmakoterapi C. Operatif FKMSocPhaRatDruUseEIS09
Farmakoterapi • Farmakokinetik • Farmakodinamik • Farmakoterapetik Efek Klinik FKMSocPhaRatDruUseEIS09
Rational Drug Use Efficacy Safety Suitability Cost WHO,1997 FKMSocPhaRatDruUseEIS09
Optimal therapeutic decisions • ...are based on an evaluation of the patient and assessment of the evidence for efficacy and safety of treatment • Drug PK/PD ~ pts. Focused information • Observational studies ( ADR) FKMSocPhaRatDruUseEIS09
Determination of Efficacy and safety is ongoing process Multiple randomized, double blind, controlled trials. • Important but infrequent ADR may escape detection in the randomized, controlled trials that demonstrate Efficacy and form the basis for approval of drugs for marketing Observational studies therefore are used to examine those ADR that only become apparent with widespread, prolonged use. FKMSocPhaRatDruUseEIS09
Penggunaan OBAT Secara Rasional/Bijak • Tepat Indikasi • Tepat Obat • Tepat Rejimen Dosis • Tepat Pasien • Waspada Efek Samping PANTAU!!! FKMSocPhaRatDruUseEIS09
Thank You FKMSocPhaRatDruUseEIS09