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American Academy of ozonoterapy

American Academy of ozonoterapy. Annual Meeting 2014 Dallas March 26-29 2014. OZONE THERAPY AND MULTIPLE SCLEROSIS: WHY?.

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American Academy of ozonoterapy

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  1. American Academy of ozonoterapy • Annual Meeting 2014 • Dallas March 26-29 2014

  2. OZONE THERAPY AND MULTIPLE SCLEROSIS: WHY?

  3. NIRS Test: After 1 hour from starting reinfusion O2Hb increase in the frontal lobes, despite the constancy of carotid flow: a clear sign of increased microvascular perfusion and increased reactivity of hemoglobin Levy Reinfusion

  4. NIRS signal during therapy O2Hb and HHb Thear is an increase of cerebral oxygenation for a long period , maximum from 20 minutes to 1,5 h after re-infusione .

  5. TCD signals during therapy That is small variation of hematic flow.

  6. Specific study of MS Complete analysis in time-frequency of NIRS segnals among 4 MS R-R and 5 heathy patients. Variation quantifier in time and frequency of cytocrome-c-oxidase concentration. Analysis by Principal Component Analysis program

  7. Changes of CYT-c-oxidase Bibliography • Less concentration of CYT-c among MS patients, caused by damages of mythocondrions • MS patients have cronich oxidative stress • Ozonotherapy has anti-oxidant effect  antixidant enzymes increase • Ozonoterapy may reduce oxidaditve stress in MS OUR experiment results • Low CYT-c in MS • CYT-c increases after 20’ to 40’ of reifusion • Higher level of CYT-c is a diagnostic value between MS patiens and other patiens

  8. MS: Contemporary THERAPY

  9. EDSS variactions * 4,3 3,8 * P < 0,05

  10. FREQUENCY OF RECIDIVATION/YEAR * * P < 0,05

  11. SYMPTOMATOLOGY * * * * * * * P < 0,005

  12. FOLLOW-UP 1)No patient got worse 2)All spinals reflex bladders patients got better or recovered

  13. Thanks Dr. Vincenzo Simonettiv.simonetti@tiscali.it

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