1 / 15

Introduction to the Knowledge Discovery Department Institute for Infocomm Research Limsoon Wong

Introduction to the Knowledge Discovery Department Institute for Infocomm Research Limsoon Wong Deputy Executive Director (Research). I 2 R: Imagination to reality. I 2 R Knowledge Discovery Dept: INTRODUCTION.

kamana
Download Presentation

Introduction to the Knowledge Discovery Department Institute for Infocomm Research Limsoon Wong

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Introduction to the Knowledge Discovery Department Institute for Infocomm Research Limsoon Wong Deputy Executive Director (Research) I2R: Imagination to reality

  2. I2R Knowledge Discovery Dept: INTRODUCTION

  3. mission: Advance Infocomm Technology to benefit humanity and create prosperity for S’pore core values:Dedication to excellence, passion for innovation, integrity & respect size: 350 RSEs BMRC SERC IMRE IME DSI IHPC ICES SIMTECH I2R

  4. I2R Services & Applications Communications & Devices Media Infocomm Security Knowledge Discovery E-Service Infrastructure Media Processing Media Semantics Human Computer Interaction • Cryptography • Network security • Information security • Service Composition • Service creation • Data-in-Network • Connected Home • Secure Filesystem/ DBMS • Mutimedia Signal Processing • Noise Reduction • Media Adaptation • Mixed Media Mining • Natural Language Synergy • Pervasive Media • Perceptual Human Media • Speech & Dialogue • Biometrics • Knowledge Extraction • Decision Systems • Discovery Systems Embedded Systems Radio Systems Networking Digital Wireless Lightwave • Terminal • Software Defined Radio • Transceiver system • Antenna • Radio Over Fiber • UWB • Modem Technology • Multiple Access • Smart Antenna Array Systems • Network Design • WDM Systems • Fibre Technology Organization • Next Gen IP • End-to-end QoS • Mobile Middleware • Mobile Adhoc Networks • Mobile Sensor Networks

  5. Protein Interactions Extraction (PIES) 8 years of bioinformatics R&D in Singapore MHC-Peptide Binding (PREDICT) Gene Expression & Medical Record Datamining (PCL) Molecular Connections Cleansing & Warehousing (FIMM) Integration Technology (Kleisli) Gene Feature Recognition (Dragon) Venom Informatics Biobase GeneticXchange 1994 1996 1998 2002 2000 ISS LIT/I2R KRDL History

  6. Objectives Translate inspiration from biological systems into advancement of life and computing sciences Advance data mining technologies in decision systems for complex problems To work on practical systems for data mining data cleansing knowledge extraction Applied to gene regulation protein interaction clinical data analysis ligand-receptor interaction in addition to non-bio areas Direction & Plan

  7. I2R Knowledge Discovery Dept: RECENT ACCOMPLISHMENTS

  8. Vaccines are often the only solution for viral diseases Finding & developing effective vaccine targets (epitopes) is slow and expensive process Predict Epitopes,Find Vaccine Targets • Develop systems to recognize • protein peptides that bind • MHC molecules • Develop systems to recognize • hot spots in viral antigens

  9. Effective recognition of initiation, control, and termination of biological processes is crucial to speeding up and focusing scientific experiments Data mining of bio seqs to find rules for recognizing & understanding functional sites Dragon’s 10x reduction of TSS recognition false positives Recognize Functional Sites,Help Scientists

  10. Diagnose Leukaemia, Benefit Children • Childhood leukaemia is a heterogeneous disease • Treatment is based on subtype • 3 different tests and 4 different experts are needed for diagnosis • Curable in USA, • fatal in Indonesia Cancer Cell, 1:133-143, 2002 • A single platform diagnosis • based on gene expression • Data mining to discover • rules that are easy for • doctors to understand

  11. Understand Proteins,Fight Diseases • Understanding function and role of protein needs organised info on interaction pathways • Such info are often reported in scientific paper but are seldom found in structured databases • Knowledge extraction • system to process free text • extract protein names • extract interactions Jak1

  12. FANTOM2 Consortium Nature 420, 563-573, 2002 Recent Collaborations/Partners • Molecular Connections, India • RIKEN, Japan • St Jude, USA • BioBase, Germany • Canberra Hosp., Australia • GIS, Singapore

  13. I2R Knowledge Discovery Dept: PEOPLE

  14. Limsoon Wong Vladimir Bajic See-Kiong Ng Vladimir Brusic Jinyan Li Who will you be working with... Heads of labs Other PIs • 18 full-time staff comprising 9 PhD, 6MSc, and 3BSc • Our faculty holds adjunct professorial positions in SANBI, Univ. of Canberra, NUS, and NTU

  15. Journals: 3 chief editorial roles, and 9 editorial board memberships International Conferences (last 5 years): 4 conference chairs, and more than 40 program committee roles, 10 keynote lectures, and dozens of plenary talks Publications (last 5 years):More than 100 in last 5 years, mostly in reputable journals (e.g. Nature, PNAS, Cancer Cell, JACM) and top conferences. Patents (last 5 years): 1 granted and 6 pending Commercialization (last 5 years): 2 international start-ups and one software licensed Track Record

More Related