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IN THE NAME OF GOD. Dr Mohammad Talebpour Advanced Laparoscopic Fellowship Tehran University of Medical Science. THE ROLE OF BARIATRIC SURGERY IN INFERTILITY AND PERIODIC CYCLE. Disease Incidence Gynecologic comorbidity : Infertility Periodic cycle Sexual activity
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Dr Mohammad Talebpour Advanced Laparoscopic Fellowship Tehran University of Medical Science THE ROLE OF BARIATRIC SURGERY IN INFERTILITY AND PERIODIC CYCLE
Disease • Incidence • Gynecologic comorbidity: Infertility Periodic cycle Sexual activity • Surgery: Restrictive (TVGP) Malabsorptive (GB, very rare in female) • Aim: Assessment the role of bariatric surgery in gynecologic comorbidity MORBID OBESITY
Patient selection: (2002 to 2008): BMI>40 BMI>35 with co morbidity like diabetes and so on) • Patient subdivision: Postmenopouse(A) Premenopouse married (B) Premenopouse virgin (C) • Technique of choice: Morbid obesity: Total gastric vertical plication (TGVP) Super obesity: TGVP or Gastric Bypass • Changes of infertility or irregularity of periodic cycle recorded at least during first year of operation. MATERIAL & METHOD
Laparoscopic • Conservative • Low price • Reversible • Volume residue: 50 cc • EWL: 60% during 6 month • Unrelated to technique morbidity: 2% • Reoperation: 2% • High cooperation in female • Safe alternative between restrictive operations ADVANTAGES OF TVGP
Supine position • Trocars: 10 mm (one), 5 mm (three) • Ergonomy • Greater curvature release by ligature • Angle of Hiss preserve • Plication at greater curvature by continuous suture 00 nylon • From cardia to 5 cm of pylorus METHOD OF TGVP
False positive sense of thirsty • Effective volume of stomach: 50 cc • Pain or reflux secondary to more intake: Inhibitory effect • Gradually dilation of remnant volume (4 years) 50 cc to 200 cc • Psychological control to continue diet RESULT OF METHOD
RESULT 300 cases during 6 years 254 female (mean age of 30 years old and mean BMI of 43) Follow up of 47 cases was impossible (29 female) Mean excessive weight loss : 1 month 20% EWL 6 months 60% EWL 12 months 75% EWL In 220 cases technique of choice was TGVP and in remaining it was bypass (5 cases).
RESTRICTIVE: EARLY MORBID OBESITY WITH COOPERATION (262 TVGP), 249 FEMALE: 220 WITH FOLLOW UP • MIXED: LATE MORBID OBESITY WITH COOPERATION (24 GB), 4 FEMALE OMEGA ANASTHOMOSIS CONTINOUS HAND SWEN NYLON 00 • MALABSORPTIVE: MORBID OBESITY WITHOUT COOPERATION (14 ILEOJEJUNAL BYPASS), 1 FEMALE TECHNIQUE SELECTION
group A: 21 (mean age 52 years, mean BMI 45) • group B: 69 (mean age 34 years, mean BMI 44) 30cases (43%) complained of irregular cycle 14 cases (20%) were infertile (>6 months failure) • group C: 135 (mean age 25, mean BMI 42) 57 cases of group C (42%) complained of irregular cycle. result
Infertility: 10cases of infertile group got pregnant (71%) after one year of operation • Periodic cycle: In 24 cases of group B (80%) and 46 cases of group C (81%) periodic cycle got regular at the end of one year (after one month the first case got regular) • PCO: 27 cases of this group were known cases of polycystic ovary (PCO) and in 16 of them regular cycle after operation recorded RESULT
Rate of infertility (20%) and irregular cycle (42%) in morbid obese female is higher than general population • The main option for treatment of this problem is weight loss with good response (71% and 81%) • After one year of weight loss other options of treatment is advised. CONCLUSION