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Dog with Acute Abdominal Pain. Dennis B. DeNicola, DVM, PhD, DACVP Chief Veterinary Educator IDEXX Laboratories. “Cookie”. 8 years old Intact Female Sheltie dog Presented with clinical history of acute abdominal pain. “Cookie” - 8 Year-old, Sheltie.
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Dog with Acute Abdominal Pain Dennis B. DeNicola, DVM, PhD, DACVP Chief Veterinary Educator IDEXX Laboratories
“Cookie” • 8 years old • Intact Female • Sheltie dog • Presented with clinical history of acute abdominal pain
“Cookie” - 8 Year-old, Sheltie WBC = 18.84 K/L HIGH ( 5.50 – 16.90 ) LYM = 0.98 K/L ( 0.70 – 4.90 ) MONO = 2.90 K/L HIGH ( 0.10 – 1.40 ) NEU = 14.67 K/L HIGH ( 2.00 – 12.00 ) EOS = 0.25 K/L ( 0.10 – 1.49 ) BASO = 0.04 K/L ( 0.00 – 0.10 ) %LYM = 5.2 % %MONO = 15.4 % %NEU = 77.8 % %EOS = 1.3 % %BASO = 0.2 % HCT = 49.2 % ( 37.0 – 55.0 ) RBC = 7.21 M/L ( 5.50 – 8.50 ) HGB = 14.8 g/dL ( 12.0 – 18.0 ) RETIC = 22.8 K/L %RETIC = 0.3 % MCV = 68.3 fL ( 60.0 – 72.0 ) RDW = 19.9 % HIGH ( 14.7 – 17.9 ) MCHC = 30.1 g/dL LOW ( 31.0 – 37.0 ) MCH = 20.54 pg ( 19.50 – 24.50 ) PLT = 329 K/L ( 175 – 500 ) MPV = 16.69 fL PCT = 0.5 % PDW = 19.2 %
“Cookie” - 8 Year-old, Sheltie Erythron HCT = 49.2 % ( 37.0 – 55.0 ) RBC = 7.21 M/L ( 5.50 – 8.50 ) HGB = 14.8 g/dL ( 12.0 – 18.0 ) RETIC = 22.8 K/L %RETIC = 0.3 % MCV = 68.3 fL ( 60.0 – 72.0 ) RDW = 19.9 % HIGH ( 14.7 – 17.9 ) MCHC = 30.1 g/dL LOW ( 31.0 – 37.0 ) MCH = 20.54 pg (19.50 – 24.50 )
“Cookie” - 8 Year-old, Sheltie Erythron HCT = 49.2 % ( 37.0 – 55.0 ) RBC = 7.21 M/L ( 5.50 – 8.50 ) HGB = 14.8 g/dL ( 12.0 – 18.0 ) RETIC = 22.8 K/L %RETIC = 0.3 % MCV = 68.3 fL ( 60.0 – 72.0 ) RDW = 19.9 % HIGH ( 14.7 – 17.9 ) MCHC = 30.1 g/dL LOW ( 31.0 – 37.0 ) MCH = 20.54 pg (19.50 – 24.50 )
“Cookie” - 8 Year-old, Sheltie Erythron HCT = 49.2 % ( 37.0 – 55.0 ) RBC = 7.21 M/L ( 5.50 – 8.50 ) HGB = 14.8 g/dL ( 12.0 – 18.0 ) RETIC = 22.8 K/L %RETIC = 0.3 % MCV = 68.3 fL ( 60.0 – 72.0 ) RDW = 19.9 % HIGH ( 14.7 – 17.9 ) MCHC = 30.1 g/dL LOW ( 31.0 – 37.0 ) MCH = 20.54 pg (19.50 – 24.50 ) • Normal red blood cell density • Probable insignificant RDW and MCHC changes since other parameters are not affected
“Cookie” - 8 Year-old, Sheltie Leukon WBC = 18.84 K/L HIGH ( 5.50 – 16.90 ) LYM = 0.98 K/L ( 0.70 – 4.90 ) MONO = 2.90 K/L HIGH ( 0.10 – 1.40 ) NEU = 14.67 K/L HIGH ( 2.00 – 12.00 ) EOS = 0.25 K/L ( 0.10 – 1.49 ) BASO = 0.04 K/L ( 0.00 – 0.10 ) %LYM = 5.2 % %MONO = 15.4 % %NEU = 77.8 % %EOS = 1.3 % %BASO = 0.2 %
“Cookie” - 8 Year-old, Sheltie Leukon WBC = 18.84 K/L HIGH ( 5.50 – 16.90 )
“Cookie” - 8 Year-old, Sheltie Leukon WBC = 18.84 K/L HIGH ( 5.50 – 16.90 ) • Leukocytosis • Minimal
“Cookie” - 8 Year-old, Sheltie Leukon WBC = 18.84 K/L HIGH ( 5.50 – 16.90 ) LYM = 0.98 K/L ( 0.70 – 4.90 ) MONO = 2.90 K/L HIGH ( 0.10 – 1.40 ) NEU = 14.67 K/L HIGH ( 2.00 – 12.00 ) EOS = 0.25 K/L ( 0.10 – 1.49 ) BASO = 0.04 K/L ( 0.00 – 0.10 ) %LYM = 5.2 % %MONO = 15.4 % %NEU = 77.8 % %EOS = 1.3 % %BASO = 0.2 % • Leukocytosis • Minimal
“Cookie” - 8 Year-old, Sheltie Leukon WBC = 18.84 K/L HIGH ( 5.50 – 16.90 ) LYM = 0.98 K/L ( 0.70 – 4.90 ) MONO = 2.90 K/L HIGH ( 0.10 – 1.40 ) NEU = 14.67 K/L HIGH ( 2.00 – 12.00 ) EOS = 0.25 K/L ( 0.10 – 1.49 ) BASO = 0.04 K/L ( 0.00 – 0.10 ) %LYM = 5.2 % %MONO = 15.4 % %NEU = 77.8 % %EOS = 1.3 % %BASO = 0.2 % • Leukocytosis • Minimal • Mild monocytosis and minimal neutrophilia • Low normal lymphocytes
Leukogram Interpretation • Minimal leukocytosis • Mild monocytosis • Either tissue demand for macrophages of glucocorticoid influence • Minimal neutrophilia • Either mild inflammation or glucocorticoid influence
Leukogram Interpretation • Minimal leukocytosis • Mild monocytosis • Either tissue demand for macrophages of glucocorticoid influence • Minimal neutrophilia • Either mild inflammation or glucocorticoid influence • Blood film complement • Inflammation (left shift and toxicity in neutrophils) • Probable tissue demand for macrophages • Probable glucocorticoid influence
“Cookie” - 8 Year-old, Sheltie WBC = 18.84 K/L HIGH ( 5.50 – 16.90 ) LYM = 0.98 K/L ( 0.70 – 4.90 ) MONO = 2.90 K/L HIGH ( 0.10 – 1.40 ) NEU = 14.67 K/L HIGH ( 2.00 – 12.00 ) EOS = 0.25 K/L ( 0.10 – 1.49 ) BASO = 0.04 K/L ( 0.00 – 0.10 ) %LYM = 5.2 % %MONO = 15.4 % %NEU = 77.8 % %EOS = 1.3 % %BASO = 0.2 % HCT = 49.2 % ( 37.0 – 55.0 ) RBC = 7.21 M/L ( 5.50 – 8.50 ) HGB = 14.8 g/dL ( 12.0 – 18.0 ) RETIC = 22.8 K/L %RETIC = 0.3 % MCV = 68.3 fL ( 60.0 – 72.0 ) RDW = 19.9 % HIGH ( 14.7 – 17.9 ) MCHC = 30.1 g/dL LOW ( 31.0 – 37.0 ) MCH = 20.54 pg ( 19.50 – 24.50 ) PLT = 329 K/L ( 175 – 500 ) MPV = 16.69 fL PCT = 0.5 % PDW = 19.2 %