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Echocardiography. Post Cardiac Transplant Surgery. Post-Cardiac-Transplant Surgery. Goal Assessment of cardiac anatomy and physiology. Noninvasive early diagnosis of transplant rejection. Diagnosis of post transplant Coronary artery disease. Post-Cardiac-Transplant Surgery.
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Echocardiography Post Cardiac Transplant Surgery
Post-Cardiac-Transplant Surgery Goal • Assessment of cardiac anatomy and physiology. • Noninvasive early diagnosis of transplant rejection. • Diagnosis of post transplant Coronary artery disease
Post-Cardiac-Transplant Surgery Clinical Problems Encountered • Pericardial effusion • RV systolic dysfunction • LV systolic dysfunction
RV Systolic Dysfunction • Inadequate myocardial preservation at time of transplantation. • Persistently elevated pulmonary vascular resistance. • Transplant rejection.
LV Systolic Dysfunction • Inadequate myocardial preservation at time of transplantation. • Acute rejection. • Superimposed Coronary artery disease.
Regurgitation MR and TR Occurs secondary to: 1. Ventricular dysfunction 2. Annular dilation
Post-Cardiac-Transplant Surgery Findings in the uncomplicated Patient • Normal RV and LV size and wall thickness. • Normal systolic function.
Post-Cardiac-Transplant Surgery • Normal valvular anatomy and function – may have small amount of TR, MR and PR (prevalence similar to that in normal individual). • Abnormal septal motion is the norm.
Post-Cardiac-Transplant Surgery • Small Pericardial effusion (few weeks) • Persistently elevated PAP • Biatrial enlargment • Atrial suture line
Post-Cardiac-Transplant Surgery Abnormal Septal Motion • Anterior motion of the septum in systole. • Reduced systolic thickening of the septal myocardium.
Echo Approach • Similar to any patient • Look for suture line • Expect abnormal septal motion • Search for loculated pericardial effusion
Transplant Rejection • Increased LV mass • Decrease in systolic function • An increase in the echogenicity of the myocardium
Post-Cardiac-Transplant Surgery Transplant Rejection associated with • Restrictive ventricular filling pattern. • Decreased IVRT • Increased E wave • Decreased A wave • Shortened PHT • Loss of forward systolic flow in the SVC