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DIGESTIVE SYSTEM. Associated Glands: Salivary glands. Liver. Pancreas. LIVER. CLASSIC HEPATIC LOBULE: Hexagonal. Has portal areas at the corners and a central vein in the center. LIVER. Portal areas contain: A bile duct . A branch of hepatic artery . A branch of portal vein .
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DIGESTIVE SYSTEM • Associated Glands: • Salivary glands. • Liver. • Pancreas.
LIVER CLASSIC HEPATIC LOBULE: • Hexagonal. • Has portal areas at the corners and a central vein in the center.
LIVER • Portal areas contain: • A bile duct. • A branch of hepatic artery. • A branch of portal vein. • Connective tissue.
LIVER Structure of Lobules: • Plates of liver cells (hepatocytes). • Between the plates of hepatocytes there are blood sinusoids lined by endothelial cells and Kupffer cells (macrophages).
PANCREAS • Pancreas is a mixed gland: • Exocrine part (acini & ducts): produces digestive pancreatic enzymes. • Endocrine part (islets of Langerhans): produces hormones.
PANCREAS Pancreatic acini: • Serous acini with centroacinar cells (the beginning of the ducts). • Nuclei are basal. • Cytoplasm: • Basal part basophilic (due to abundant rER). • Apical part acidophilic (due to secretory granules).
PANCREAS Islets of Langerhans: • Pale spherical vascularized collections of endocrine cells. • Formed of 5 types of cells: • α (A) cells: secrete glucagon. • β (B) cells: secrete insulin. • δ (D) cells: secrete somatostatin. • G cells: secrete gastrin. • PP cells: secrete pancreatic polypeptide.