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5th IgCLL Educational Workshop Program

____________________________________________________________ Immunoglobulin Sequence Analysis in Chronic Lymphocytic Leukemia ____________________________________________________________. 26. 9. – 27. 9. 2013 , Hotel International, Husova 16, Brno, Czech Republic.

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5th IgCLL Educational Workshop Program

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  1. ____________________________________________________________ Immunoglobulin Sequence Analysis inChronic Lymphocytic Leukemia ____________________________________________________________ 26. 9. – 27. 9. 2013, Hotel International, Husova 16, Brno, Czech Republic Wednesday 25 September 2013Program ____________________________________________________________ 19:00Welcome dinner for invited speakers (Hotel International) Thursday 26 September 2013 ____________________________________________________________ 8:50SarkaPospisilova(CEITEC MU; University Hospital Brno; CZ) Welcome Keynote Lecture 9:00 Nicholas Chiorazzi(The Feinstein Institute for Medical Research, New York, US) The turbulent life history of CLL Session I - Modern prognostication in CLL ChairSarkaPospisilova(CEITEC MU; University Hospital Brno; CZ) 9:45Richard Rosenquist(Uppsala University, Uppsala, SWE) The genomic landscape of CLL 10:10Kostas Stamatopoulos(G. PapanicolaouHospital, Thessaloniki, GR) Immunogenetics and prognostication 10:35 PaoloGhia(UniversitaVita-Salute San Raffaele, Milano, IT) Biological prognostic markers: a critical reappraisal 11:00Coffee break 5th IgCLLEducationalWorkshop Program

  2. 5th IgCLLEducationalWorkshop Program Session II - IG sequence analysis in CLL: technical aspects ChairRichard Rosenquist(Uppsala University, Uppsala, SWE) 11:30Frederic Davi(HðpitalPitié-Salpêtrière, Paris, FR) Mechanisms of immunoglobulin diversity 11:50 Anton Langerak(University Medical Center, Rotterdam, NL) From the patient to the sequence: Primers, PCR, Detection of clonality, Sequencing 12:20 Marie-PauleLefranc(UniversitéMontpellier, Montpellier, FR) Online tools for Interpretation of IG sequences and navigation through the IMGT web- resources 12:50 Lunch Session III - Interpretation of IG sequences ChairAnastasia Hadzidimitriou(Centre for Research &Technology Hellas, Thessaloniki, GR) 14:00 Veronique Giudicelli(Université Montpellier, Montpellier, FR) How to use the IMGT/V-QUEST tool 14:30 Basic exercises I 15:15 Solutions Karla Plevova(CEITEC MasarykUniversity; University Hospital Brno; CZ) 15:45 Coffee break 16:15 Basic exercises II 17:00 Solutions VasilisBikos(CEITEC Masaryk University, CZ) 18:00 Visit to Mendel Museum, social event

  3. 5th IgCLLEducationalWorkshop Program Friday 27 September 2013 ____________________________________________________________ Session IV - Interpretation of IG sequences: advanced exercises ChairChrysoulaBelessi(General HospitalofNikea, Athens, GR) 8:30Advanced exercisesI 9:15 Solutions Lesley Ann Sutton (Uppsala University, Uppsala, SWE) 9:45 Advanced exercisesII 10:30 Solutions Andreas Agathangelidis(Università Vita-Salute San Raffaele, Milano, IT) 11:00Coffee break Session V - IG sequence analysis for everyone ChairPaolo Ghia(Universita Vita-Salute San Raffaele, Milano, IT) 11:30 Richard Rosenquist(Uppsala University, Uppsala, SWE) How to report IG sequence data in clinical routine 11:50KathleenPotter (University of Southampton, Southampton, UK) Methodological harmonization, guidance Session VI - Where do we go now? ChairKostas Stamatopoulos(G. Papanicolaou Hospital, Thessaloniki, GR) 12:10 Fiona Murray (Uppsala University, Uppsala, SWE) Recombinant antibodies in autoimmunity and malignancy: a key to improved understanding of immune processes 12:30 Anton Langerak(University Medical Center, Rotterdam, NL) Immunogenetics in the NGS era: challenges and limitations 12:50 SarkaPospisilova(CEITEC MU; University Hospital Brno; CZ) Concluding remarks 13:00Lunch

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