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91. Cell Reproduction Notebook Check 92. Karyotype Lab (graded) 93. Intro to Genetics Reading Guide (stamped) 94. Genetics Notes 95. Punnett Squares 96. More Punnett Square Practice 97. Exceptions to Mendel’s Rules 98. Oompah Loompa’s 99. Progress Report #6 100. POP QUIZ!
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91. Cell Reproduction Notebook Check • 92. Karyotype Lab (graded) • 93. Intro to Genetics Reading Guide (stamped) • 94. Genetics Notes • 95. Punnett Squares • 96. More Punnett Square Practice • 97. Exceptions to Mendel’s Rules • 98. OompahLoompa’s • 99. Progress Report #6 • 100. POP QUIZ! • 101. Pedigrees (a & b) • 102. Ugly Baby Lab • 103. Genetic Disorders
Homework!! • Finish Genetic Disorders #103 • 3/29 & 3/30 Genetics Unit TEST!
AMNIOCENTESIS a medical procedure used to diagnose chromosomal disorders in a developing fetus. A small amount of amniotic fluid, which contains fetal tissues, is extracted from the amniotic sac surrounding a developing fetus, and the DNA is examined.
GENETICS #94 • Gregor Mendel = father of heredity • Mid 1800s • Studied garden pea plants (because they could produce purebredindividuals) • Studied how traits were passed from one generation to the next
Mendel came up with several important concepts • Parents pass on genes • For each trait, an organism has 2 genes (1 allele from Mom and 1 from Dad) • Alleles can be dominant and recessive • Tall plants could equal TT or Tt, short = tt • Genotype= genetic make-up for trait (TT) • Phenotype= physical look of trait (tall)
Law of Dominance • If organisms contain two identicalalleles for a trait, it shows that trait. • Curly hair = HH • Straight hair = hh • If organisms contain two differentalleles for a trait, it shows the dominant trait. • Curly hair = Hh Homozygous alleles heterozygous alleles
Punnett Squares Used to predict the possible combinations of dominant and recessive alleles in the offspring. Genotypic ratio = 1 RR : 2 Rr : 1 rr Phenotypic ratio = 3 pink : 1 yellow
Determining Gender! • Dad = XY, some sperm have X, some have Y • Mom = XX, all eggs have X because that’s all Mom has to donate • Who determines gender of baby – Mom or Dad?
Law of Independent Assortment The genes for traits found on different chromosomes separate independently when gametes are made.
Test Cross A deliberate genetic cross with a homozygous recessive individual that can be used to determine whether an organism is homozygous or heterozygous dominant for a trait. ?
Phenotype is a mix of geneticsand environment Nature vs. Nurture Debate
#96 More Punnett Square Practice (make Punnett Squares & describe offspring using genotypic and phenotypic ratios) • Green pea plant (GG) X Green pea plant (Gg) • Tall plant (TT) X short plant (tt) • Two tall plants (Tt) • Two white flowers (white = recessive) • Homozygous red flower X white flower • Homozygous dominant brown mouse X heterozygous brown mouse (tan = recessive) • Heterozygous white rabbit X black rabbit. • Two heterozygous white rabbits. (black = rec) • How would you figure out if a purple plant (dominant) is heterozygous vs. homozygous?
GENOTYPIC RATIO PHENOTYPIC RATIO
Exceptions to Mendel’s Rules Sometimes genetics isn’t always as simple as Mendel’s Law of Dominance #97
Incomplete Dominance • Heterozygote is a BLEND of the 2 homozygotes • RR = red flowers • rr = white flowers • Rr = PINK flowers • Cross two pink flowers. • Genotypic ratio 1:2:1 • Phenotypic ratio 1 red: 2 pink: 1 white
Codominance • Heterozygote show BOTH traits • BB = black cows • WW = white cows • BW = black & white • BB X WW • All BW offspring • Genotypic ratio = 0:4:0 • Phenotypic ratio = 0:4:0
Multiple Alleles • Traits that have more than two alleles. • Blood types – • 3 alleles • A and B are co-dominant • O is recessive to A and B • 4 phenotypes • 1)Type A • blood contains “A” proteins • genotype: AA or AO
2) Type B • blood contains “B” proteins • (genotype: BB or BO) • 3)Type AB • blood contains both proteins • genotype: AB • 4) Type O • neither protein present in blood • Genotype: OO • AB is an example of ________________.
Polygenic Inheritance • Several genes are inherited from each parent for 1 trait. • Many possible phenotypes. • Examples: skin color, eye color, height, weight • ABC, ABc, AbC, aBC = dark • abc, abC, Abc, aBc= light
Sex-Linked Traits • Located on X chromosome • Females are only carriers • Mostly males are affected • Colorblindness, hemophilia, baldness • XBXB = normal female • XBXb= carrier female • XbXb= colorblind female • XBY= normal male • XbY= colorblind male • Cross a carrier female with a normal male. Explain the possible offspring.