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BLOOD. FUNCTION. TRANSPORT NUTRIENTS, WASTES, GASES REGULATE FLUID AND ELECTROLYTE, ACID-BASE, AND BODY TEMPERATURE PROTECT AGAINST PATHOGENS. CHARACTERISTICS OF BLOOD. AMOUNT COLOR pH VISCOSITY. CONTENTS OF BLOOD. PLASMA LIQUID PORTION, APPROX 91% IS WATER BLOOD CELLS INCLUDING
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FUNCTION • TRANSPORT NUTRIENTS, WASTES, GASES • REGULATE FLUID AND ELECTROLYTE, ACID-BASE, AND BODY TEMPERATURE • PROTECT AGAINST PATHOGENS
CHARACTERISTICS OF BLOOD • AMOUNT • COLOR • pH • VISCOSITY
CONTENTS OF BLOOD • PLASMA • LIQUID PORTION, APPROX 91% IS WATER • BLOOD CELLS INCLUDING 1. RBC 2. WBC 3. PLATELETS
BLOOD CELL PRODUCTION • PRODUCED IN HEMOPOIETIC TISSUES (RED BONE MARROW) AND LYMPHATIC TISSUE (SPLEEN, LYMPH NODES) • BONE MARROW CONTAINS STEM CELLS (PRECURSOR CELLS)
STEM CELLS • VITAMIN B12 AND FOLIC ACID ARE NECESSARY FOR DNA SYNTHESIS IN THE STEM CELLS
RBC AKA ERYTHROCYTES • BICONCAVE, CIRCULAR • MATURE RBC HAVE NO NUCLEI • FUNCTIONS IS TO CARRY OXYGEN ON THE HEMOGLOBIN (Hgb) • IRON IS ESSENTIAL IN THE FORMATION OF Hgb
RBC AKA ERYTHROCYTES DID YOU KNOW… THE BODY MAKES SEVERAL MILLION NEW RBC/SECOND RBC’s LIVE APPROX 120 DAYS
RBC DEATH • THE IRON PORTION IS REABSORBED AND STORED BY THE LIVER • THE HEME PORTION IS A WASTE PRODUCT
BLOOD TYPES • O, A, B, AB • O IS UNIVERSAL DONOR • AB IS UNIVERSAL RECIPIENT • IF GIVEN THE WRONG BLOOD TYPE, AGGLUTINATION AND HEMOLYSIS OCCURS
Rh FACTOR • AN ANTIGEN PRESENT IN THE BLOOD • ERYTHROBLASTOSIS FETALIS
WBC AKA LEUKOCYTES • FUNCTION IS TO PROTECT THE BODY FROM INFECTION AND TO PROVIDE IMMUNITY • LARGE THAN RBC AND CONTAIN A NUCLEUS
5 TYPES OF WBC • EOSINOPHILS – DETOXIFY FOREIGN PROTEINS • BASOPHILS – CONTAIN HEPARIN AND HISTAMINE • NEUTROPHILS AND MONOCYTES – PHAGOCYTIZE PATHOGENS • LYMPHOCYTES PRODUCE ANTIBODIES
PLATELETS AKA THROMBOCYTES • HEMOSTASIS (PREVENTION OF BLOOD LOSS) • PROVIDES CLOTTING BY 1. VASCULAR SPASM (FOR LARGE VESSELS) 2. PLATELET PLUG (FOR CAPILLARY RUPTURE) 3. CHEMICAL CLOTTING – CLOT FORMS IN A SERIES OF STEPS
TERMS • THROMBUS – CLOT • EMBOLISM – A MOVING CLOT