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Integumentary System. Membranes. Thin, sheet-like structures that: Cover and protect body surfaces Line body cavities Line hollow organs Cover organs Anchor organs Reduce friction. Epithelial Membranes. Composed of Epithelial tissues and specialized connective tissue
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Membranes • Thin, sheet-like structures that: • Cover and protect body surfaces • Line body cavities • Line hollow organs • Cover organs • Anchor organs • Reduce friction
Epithelial Membranes • Composed of Epithelial tissues and specialized connective tissue • Three types of Epithelial membranes • Cutaneous • Serous • Mucous
Cutaneous • Primary organ of the integumentary system (Skin) • Makes up roughly 16% of total body weight • Three main functions of skin • Prevents infection • Prevents desiccation • Thermoregulation
Serous • Found only on surfaces of closed cavities - Parietal: lines body cavities - Visceral: cover surface of organs - Pleura: Serous membranes in the thoracic cavity - Peritoneum: Serous membranes in the abdominal cavity
Mucous • Epithelial membranes that line body surfaces opening directly to the exterior • Respiratory tract • Digestive tract • Urinary tract • Reproductive tract
Mucous (cont.) • Mucocutaneous junction – “Fusion” where skin and mucous membranes meet. • Junctions lack accessory organs such as sweat glands and hair • Eyelids and nasal openings are examples
Connective Membranes • Composed of connective tissue only • Synovial membrane
Synovial membrane • Lines the spaces between bones and joints • Smooth , slick and secrete lubricating synovial fluid
Epidermis • Outermost layer of skin, contains stratum germinativum and stratum corneum
Stratum Germinativum • Undergo mitosis and reproduce themselves • Move towards the surface and specialize • Cells contain cytoplasm • Melanocytes produce melanin to protect from U.V.
Movement through the Epidermis • Cells move upward from stratum germinativum to stratum corneum (2-4 weeks)
Stratum Corneum • Tough outer layer of epidermis • Cytoplasm in cells are replaced by keratin • Tough and waterproof • Roughly 40,000 cells are lost per minute • 10 lbs per year!!
Dermal-epidermal junction • Thin area “glues” epidermis to dermis • If this area is damaged, blisters form
Hair shaft Sudoriforis gland
Dermis • Mostly connective tissue • Stretchable and elastic • Fingerprints develop here (dermal papillae) • Most of the appendages of skin are located here.
Appendages of Skin • Hair Follicles - layer of skin that holds the hair • Papilla of Hair – site of hair growth • Hair Shaft- visible part of hair • Arrector Pili – muscle attached to hair (goose bumps) • Meissner’s Corpuscle – senses light touch • Sebaceous Glands – secrete oil (sebum) to prevent the skin from drying • Sudoriforis Glands
Sudoriferous Glands • Eccrine • Most numerous • Distributed over the total body surface • Produce perspiration • Eliminates ammonia and uric acid • Maintains constant temperature • Apocrine • Found in armpit and around the genitals • Secrete thicker, milky secretion
Subcutaneous Fatty Tissue • Insulates the body from extremes of heat and cold • Source of stored NRG • Pads and protects underlying tissues
Functions of Integumentary System • Protection • Thermoregulation * • Prevent infection * • Sense organ activity • Prevent desiccation *
Lesions • Any measurable variation from the normal structure of skin • Freckles • Warts • Blisters • Scratch • Acne
Burns • Damage to the skin resulting from: • Extreme heat • Extreme cold • Overexposure to U.V. rays • Contact with electric current • Chemicals
1st degree • Minor discomfort • Reddening of skin • Mostly epidermis damaged • Tissue destruction minimal • Example - sunburn
2nd degree • Blisters • Severe pain • Damage to appendages of skin • Deep epidermis and dermis damaged
3rd degree • Complete destruction of the epidermis, dermis, and part of the SCFT • Lesions are insensitive to pain • Patients rarely die from the burn itself (complications)
Used to determine the extent of a burn “Rule of Nines”
Infections • The skin is the body’s first line of defense so it is commonly infected • Impetigo: staph infection • Tinea: Ringworm, jock itch, athlete’s foot • Warts: caused by the papilloma virus
Skin Cancer • Abnormal cells reproduce uncontrollably • Risk factors include: • Genetic predetermination • Excessive exposure to UV radiation • Stress
Squamous cell carcinoma • Most common type of skin cancer • Slow growing • Cancer will metastasize (invade other organs) if not treated
Basal cell carcinoma • Usually occurs on the upper face • Begins at basal layer of stratum germinativum • Less likely to metastasize than other skin cancers
Melanoma • Most serious form of skin cancer • Causes death in 1:4 cases • Often develops from moles