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The two Valleys of Death in Technology Commercialization IEEE Life Sciences Grand Challenges

The two Valleys of Death in Technology Commercialization IEEE Life Sciences Grand Challenges Singapore December 2013. Bijan Dorri. Outline Product Development Steps Two Valleys of Death Real Life Examples Guidelines. Step 1 - Technology Development : Retiring Technical Risks.

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The two Valleys of Death in Technology Commercialization IEEE Life Sciences Grand Challenges

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  1. The two Valleys of Death in Technology Commercialization IEEE Life Sciences Grand Challenges Singapore December 2013 Bijan Dorri

  2. Outline • Product Development Steps • Two Valleys of Death • Real Life Examples • Guidelines

  3. Step 1 - Technology Development : Retiring Technical Risks • Basic Research • Discovery • Invention Doing it Once! – Prototype

  4. Step 2- Product Development : Retiring Produciblity & Regulatory Risks • Detail Design • Manufacturing & Supplier Development • Clinical Trials • Regulatory Approvals Can Make Many & Has Permission to Market

  5. Step 3- Commercialization: Retiring Market Risks • Market Validation • Market Creation • Re-imbursement Profitable Product

  6. Two Valleys of Death Regulatory Re-imbursement Patenting Product Development Market Creation Technology Development Valley of Death 2 Clinical Trials Basic Research Discovery Valley of Death 1 Product Design Commercialization Product Development Technology Development

  7. 5 Real Life Examples 3 4 2 1 5 Breast Tomosynthesis Pocket Ultrasound 64 Slice CT Cardiac CT MR Surgery Limb MRI 2000 1992 2010 2005 1994 New Clinical Utilization of Existing Product Tech Died in DV1 Going through DV2 Unmet Clinical Need Immediate Market No DV1 or 2 Changing Clinical Practice Died in DV2 Replacing Existing Product 10 Years in DV2 Replacing Existing Product 20 Years in DV2

  8. Technology Portfolio Management Pocket Size Ultrasound New Detector for CT Technology Risk Affordable Accessible ECG New SW for Clinical Decision Market Risk

  9. Investment Guidelines • Innovation Type • Solves Unmet Clinical Need • Under the hood of existing product • Replaces Existing Product • Changes Clinical Practice DV1 $ $ $$ $$ DV2 $ 0 $$ $$$

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