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Dr. Egils Praulitis, UWE, Jan 2010

Dr. Egils Praulitis, UWE, Jan 2010. European Commission Perspective. Universities are crucial for training for jobs and in developing and transferring knowledge to the commercial market place

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Dr. Egils Praulitis, UWE, Jan 2010

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  1. Dr. Egils Praulitis, UWE, Jan 2010

  2. European Commission Perspective • Universities are crucial for training for jobs and in developing and transferring knowledge to the commercial market place • Universities are also major agents in providing an education background towards the development of entrepreneurial attitudes and skills. • Entrepreneurs are viewed as engines of a market economy and the ventures they create serve as catalysts for technological progress • Promotion of technology transfer from the university to the marketplace through the development of technology-based business plans Dr. Egils Praulitis, UWE, Jan 2010

  3. But HOW do I get my good ideas to market ? Dr. Egils Praulitis, UWE, Jan 2010

  4. FREE and confidential 1-2-1 advice sessions with an experienced UWE Business Advisor • FREE information on starting a business and/or developing your enterprise skills • Networking opportunities with other enterprising and creative individuals • Cross-faculty support with enterprise related workshops and training Dr. Egils Praulitis, UWE, Jan 2010

  5. Find out if your HOT idea has got what it takes... What is the BizIdea? TheBizIdea is the University of the West of England's inspirational business plan competition. It encourages UWE entrepreneurs to make their business ideas a reality! From the development of an initial idea entrants are taken through to the submission of a full business plan. Finalists are then selected to pitch to a panel of experts. With three different categories (Business, Social Enterprise and Creative Design) and an additional marketing prize, there is something for everyone. Who enters theBizIdea? The competition is open to all UWE students, staff and alumni who have graduated in the last 5 years. Teams which include external members but are led by a UWE student, alumnus or staff member are also welcomed. Dr. Egils Praulitis, UWE, Jan 2010

  6. FACULTY and UWE SUPPORT for INNOVATION Dr. Egils Praulitis, UWE, Jan 2010

  7. FACULTY OF HEALTH AND LIFE SCIENCES • Research Centres • Appearance Research (CAR) • Analytical, Materials and Sensor Science (CRAMSS) • Biomedicine (CRIB) • Child and Adolescent Health (CCAH) • Clinical and Health Services Research (CHSR) • Environmental Sciences (CRES) • Learning and Workforce Research (CLWR) • Plant Science (CRIPS) • Public Health Research (CPHR) Institutes Institute of Biosensing Technology Institute for Sustainability, Health and Environment (ISHE) Dr. Egils Praulitis, UWE, Jan 2010

  8. CENTRE FOR RESEARCH IN PLANT SCIENCE (CRIPS) • Areas of research currently include: • Abscisic acid signaling • Reactive oxygen species and free radicals • Nitric oxide • Molecular genetics of plant pathogenic bacteria • Plants and radioactivity • Auxin Signaling • Temperate and tropical forest research • Downy mildews • Post-harvest spoilage • Biofuels Director: Dr Neil Willey    Dr. Egils Praulitis, UWE, Jan 2010

  9. INSTITUTE of BIO-SENSING TECHNOLOGY The first the UK - and aims to develop academic/industrial partnerships to address the technological challenges posed by each of these sectors - from the development of novel technology for detection and measurement of biological systems to the integration of biological systems into novel sensing technology. Prof Richard Luxton - Director Dr Janice Kiely - Director Dr Olena Doran - Director of Research Development Urszula Strzemiecka - Marketing Officer Dr. Egils Praulitis, UWE, Jan 2010

  10. Research Centres Universities and health trusts Institute offices and facilities Industry RDA/EDA Institute Business Development Research bidding and management Research councils Integrate research TSB Exploit research Industry Business Membership Knowledge Exchange International office European funding KTN’s Dr. Egils Praulitis, UWE, Jan 2010

  11. ACADEMIC PARTNERS Biomedical Physics Group, Exeter University Centre for Complex Cooperative Systems, UWE Bristol Centre for Innovative Manufacture and Machine Vision Systems, UWE Bristol Centre for Research in Analytical, Materials and Sensor Science, UWE Bristol Centre for Research in Biomedicine, UWE Bristol Centre for Research in Environmental Science, UWE Bristol Centre for Research in Plant Science, UWE Bristol Engineering and Medical Technology, UWE Bristol Hackensack University Medical Center (HUMC), New Jersey Network of Infection Control, UWE Bristol New Jersey Institute of Technology (NJIT) North Bristol NHS Trust Plymouth Marine Laboratory Royal United Hospital, Bath Signal Processing Group, University of Bristol University Hospitals Bristol University of Medicine and Dentistry of New Jersey Dr. Egils Praulitis, UWE, Jan 2010

  12. BUSINESS/INDUSTRIAL MEMBERS Consultancy/Service Provider La Playa Science & Technology Black Kite Staplethorne WRc Modern Water BioTech/LifeSciencesAbbott Diagnostics Atlas Genetics Axis-Shield Diagnostics Immune Macro Biotic Technology (IMBT) Lumora Q-tis Pharmaceuticals Limited Sensor Systems Biral Chelsea Technologies Group EvanesCo HazmatLINK Universal Sensors Gwent Electronic Materials Instrumentation Izon Science National Instruments Uniscan Instruments Support Organisations BioApproaches South West Environmental Knowledge Transfer Network Severnside Alliance for Translational Research (SARTRE) Sensors & Instrumentation KTN (SIKTN) Sensors for Water Interest Group (SWIG) South West RDA UKTI South West Dr. Egils Praulitis, UWE, Jan 2010

  13. EU Funded Projects • Molecular Blood Grouping and Genotyping • A UWE led consortium has completed a three-year project that aims to use genotyping to improve patient safety and blood transfusion compatibility. The project, called Bloodgen will include the launch of a CE-marked commercial product Bloodchip which will be sold to Blood Services worldwide. • Framework 6, Life Science, Integrated Project • The overall goal of Sens-it-iv is to develop strategies to replace animal experimentation by in vitro assays for identifying skin and respiratory sensitizers in relation with the use of safe ingredients by the chemical, cosmetic and pharmaceutical industry. • 31 partners, led by Danish company Novozyme Dr. Egils Praulitis, UWE, Jan 2010

  14. SCREEN PRINTED BIOSENSORS The Institute has expertise in the development of conductive inks used to screen-print novel biosensors. Inhibition of enzymes immobilised on the sensor surface has been used to produce a rapid and sensitive assay for pesticide residues on food or in water.  Other screen-printed biosensors have been developed for measuring mycotoxins in food and ammonia in water. Lead researcher: Professor John Hart UWE PARAMAGNETIC PARTICLE-BASED DETECTION SYSTEM The use of paramagnetic particles as a label in an immunoassay has resulted in the development of a rapid and highly sensitive biosensing device. Substances in the part-per-trillion concentration range have been measured. The novel instrumentation is inexpensive and can be powered by standard, small batteries to be used as a handheld system for field testing. A rapid assay system for point of care testing using paramagnetic particles as the label has also been developed and is being evaluated for use for PSA measurement. The assay can be performed on a small blood sample and the result is obtained in a few minutes. Lead researchers: Dr Richard Luxton & Dr Janice Kiely UWE Dr. Egils Praulitis, UWE, Jan 2010

  15. VAPOUR SENSING Electrochemical sensor arrays have been developed which respond to specific volatiles for the early detection of food spoilage. Examples have been the detection of rotting potatoes in storage and the identification of spoiled hams which have not been successfully cured. A new low cost, highly sensitive generic gas sensor technology has recently developed that has applications for environmental monitoring. The use of mass spectroscopy has identified novel volatile compounds from the urine of patients with prostate cancer. A small pilot study has been performed which gave 100% correct classification of 15 prostate cancer patients and 20 normal age-match patients. Currently a patent is being filed but further collaboration is being sought to undertake a larger study. The Institute has a complimentary strand of research, the diagnosis of gastrointestinal (GI) disease and infection trough volatile analysis. A broad patent application to protect this methodology as recently received a certificate of allowance from the USPTO. Prototype point of care (POC) technology is being developed to enable the recognition of the volatile markers, and a patent application has been filed on an enabling technology. Lead researcher: Professor Norman Ratcliffe UWE Dr. Egils Praulitis, UWE, Jan 2010

  16. IMPEDANCE SPECTROSCOPY A novel technology based on impedance spectroscopy has shown that characteristic, fingerprint changes can be seen in cell culture systems exposed to particular cytotoxic agents. The characteristic changes are thought to be representative of the effect of the cytotoxic agents and can give an indication of the mode of action of that agent on the cells. This technology also shows differences in the spectra between different cell types. Further collaboration to investigate the use of this technology to evaluate cytotoxic effects would be valuable. In addition, other collaborative projects could evaluate differences in impedance spectra of different types of cancer relative to healthy cells or to investigate and develop this technology into an environmental monitoring system. Lead researchers: Prof Richard Luxton & Dr Janice Kiely UWE Dr. Egils Praulitis, UWE, Jan 2010

  17. BIOLUMINESCENT REPORTER BACTERIA Bioluminescent bacteria have been developed for use as a reporter in the evaluation of sterilisation and decontamination techniques. The Institute has expertise in developing novel methods of incorporating a lux-gene cassette into a wide range of bacteria. Other applications of the bioluminescent bacteria include the detection of environmental toxins. A novel bio-assay has also been developed to predict which leukaemia patients will respond to therapy. This technology is being patented and a study to evaluate the predictive value of the test is being undertaken in conjunction with a diagnostics company and hospital specialising in the treatment of leukaemia. Collaboration to undertake wider studies of this novel technology would add benefit. Lead researcher: Dr Vyv Salisbury UWE Dr. Egils Praulitis, UWE, Jan 2010

  18. SPHEROIDS Spheroid are aggregates of cells grown in a special conditions that allows one to form spheres of tissue which mimic the organ from which the cells were taken. For example hepatic spheroids will take on many of the functions of the liver including producing bilirubin and developing bile canaliculi. Cardiac spheroids beat like a heart. These three dimensional tissue constructs are useful models to investigate the toxic effects of compounds. This can be performed through the analysis of the media in which the steroids were grown for direct analysis of the spheroids using microscopy for sensor technology. Applications for spheroids technology include drug discovery and high throughput screening, toxicity testing and environmental testing. There is high potential for the development of novel bio-sensing applications through integrating with new centre technologies. Lead researcher: Professor Simon Jackson UWE Dr. Egils Praulitis, UWE, Jan 2010

  19. FACULTY and UWE SUPPORT for INNOVATION Dr. Egils Praulitis, UWE, Jan 2010

  20. RESEARCH, BUSINESS AND INNOVATION UWE Enterprise and Innovation Pipeline External clients & sponsors Students Staff Alumni Innovations “earning their keep” development UWE IP successful commercial risk projects exploitation reduction ideas Ideas Factory Incubation SPark Pre - - incubation Grow - on Resident / Non Resident + + theBizIdea Workshops / Mentors / Professional Advisors / Networks Dr. Egils Praulitis, UWE, Jan 2010

  21. NATIONAL AND EU FUNDING BODIES Dr. Egils Praulitis, UWE, Jan 2010

  22. THE ‘SHAPE’ OF INNOVATION AND RESEARCH PROJECTS LARGE >>>>> small Dr. Egils Praulitis, UWE, Jan 2010

  23. PROMOTIING INNOVATION Dr. Egils Praulitis, UWE, Jan 2010

  24. TakingSCIENCEandINNOVATION to the MARKET PLACE Just needs a bit of organisation! Dr. Egils Praulitis, UWE, Jan 2010

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