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1. Clostridium Difficile associated diarrhoea (CDAD) Dr Farah Raza Moosvi
SHO GPVTS
Bromley
2. Clostridium Difficile Anaerobic
Spore producing
Toxin producing
3. Importance of CDAD Environmental spores community reservoir
Increased incidence in Bromley – nearly doubled in 2 years
Elderly patients (~25 % mortality)
Nursing Home
4. Risk Factors Broad Spectrum Antibiotic (BSA)
Duration of antibiotic use
PPIs
Elderly + BSA consider probiotic
Community reservoir infection control
Prolonged healthcare stay/NH
5. Antibiotics responsible Clindamycin
Augmentin
Cephalosporins
Quinolones
6. Recent Changes…e.g. at the PRUH
8. Primary Prevention Prudent antibiotic perscribing
Reduce use of BSA
Probiotics
Handwashing
Isolation
Stool MC&S
10. Bromley PCT = presently working on Clostridium Difficile action plan
11. References DoH/HPA
Journal of antimicrobial therapy
BMJ
Journal watch
Science daily
PRUH Microbiology Dept
12. ………………. We all need to play our part in help limiting the spread of CDAD…..lets make our community safer
Thank You