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Innovation in Health Care through Open Source Research. Bonnie Hurwitz Program Director for Health InformaticS. A new era in Biomedical research. An information driven science H igh -throughput experimental methods Predict complex biological processes
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Innovation in Health Care through Open Source Research Bonnie Hurwitz Program Director for Health InformaticS
A new era in Biomedical research • An information driven science • High-throughput experimental methods • Predict complex biological processes • Transformative nature of computation and large-scale data integration • Increased prioritization of “biological cyberinfrastructure”
A Developing Biomedical collaborative culture • Open standards to provide resilience to technical volatility • An extended ecosystem • Need to harmonize data between disparate systems and processes
Pieces of a biomedical cyberinfrastructure • Data infrastructure • Computational infrastructure • Communication infrastructure • Interconnecting computational and data resources • Bandwidth • Syntactic connectivity • Semantic connectivity • Human infrastructure to support collaboration
Components of Collaborative culture • Competence • Character • Collaboration • Creativity • Courage
Large-scale Biomedical collaborations Biomedical Informatics Research Network (BIRN) • 14 million per year • Funded by National Center for Research Resources in 2001 • Established for neuro-imaging data Mission: share data/tools - provide security - develop, add to, merge ontologies - query across disparate data sources - search for outside resources
Large-scale Biomedical collaborations Cancer Bioinformatics Grid (caBig) • 20 million per year • Funded by US National Cancer Institute in 2003 Mission: unite cancer centers - create a common ontology - developinterconnecting toolkits - reduce data heterogeneity
Champion innovation • Create a shared vision • Be passionate about finding “better ways” • Seek and support new ideas • Build networks of teams with strong collaboration skills, ethics, and values • Preserve trust, demonstrate integrity • Challenge established thought • Be an idea crusader