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PROTEIN PHYSICS LECTURE 7. Main secondary structures. H-bonds. Helices: Right and Left. Mirror-asymmetric amino acids – mirror-asymmetric (“chiral”) helices Right -helix. Right -helix. Right -helix Right 3 10 helix. ALA, etc. GLY only. , twisted. ,
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PROTEIN PHYSICS LECTURE 7
H-bonds Helices: Right and Left
Mirror-asymmetric amino acids – mirror-asymmetric (“chiral”) helices Right -helix
Right -helix
Right -helix Right 310 helix
, twisted
, twisted
Mirror-asymmetric amino acids – mirror-asymmetric twist of -sheets
turn I turn I’ turn II
Experimental study of secondary structure X-ray crystallography NMR spectroscopy (cross-peaks)
Experimental study of secondary structure Far UV CD spectra (peptide groups) IR spectra (amid I, C=O bond)
Membrane Globular Fibrous H-bonds & hydrophobics