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8 CRC tissues. 8 CRC tissues. 8 corresponding adjacent normal tissues. 8 corresponding adjacent normal tissues. Step 1. Step 1. both miRNA and mRNA microarray tests. both miRNA and mRNA microarray tests. 2916 deregulated mRNAs. 2916 deregulated mRNAs. 32 deregulated miRNAs.
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8 CRC tissues 8 CRC tissues 8 corresponding adjacent normal tissues 8 corresponding adjacent normal tissues Step 1 Step 1 both miRNA and mRNA microarray tests both miRNA and mRNA microarray tests 2916 deregulated mRNAs 2916 deregulated mRNAs 32 deregulated miRNAs 32 deregulated miRNAs Step 2 Step 2 Pearson correlation analysis Pearson correlation analysis for anti for anti - - correlationships correlationships 17361 significant miRNA 17360 significant miRNA - - mRNA pairs mRNA pairs TargetScan+miRnada Step 3 Step 3 72 target relationship of miRNA p 22 miRNAs 14 up 8 down p 58 mRNAs 15 up 43 down