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Analytical Ultracentrifugation. Density Gradient formed from various solutes:. ‘40s. ‘50s. RAFT MODEL. Current day. ‘70s. The hydrophobic effect:. Transfer from water to alcohol. MLVs. unilamellar vesicles. SUVs. Multilamellar vesicles. Liposomes as Membrane Mimetics. 50nm. 500nm.
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Analytical Ultracentrifugation Density Gradient formed from various solutes:
‘40s ‘50s RAFT MODEL Current day ‘70s
The hydrophobic effect: Transfer from water to alcohol
MLVs unilamellar vesicles SUVs Multilamellar vesicles
Liposomes as Membrane Mimetics 50nm 500nm 5000nm As vesicles get smaller, they tumble more quickly, have a higher surface curvature, less interior volume, are less thermodynamically stable, and less symmetry in lipid distribution