Ways to do Highly Cited Articles

1. Ways to do Highly Cited Articles Mike C.C. Chiueh, Ph.D. Editor-in-Chief The Taipei Journal of Experimental and Clinical Medicine Prof & Dean Emeritus (TMU, Pharmacy School) NIH Scientist Emeritus (LCS, NIMH) TMU, March 7, 2012

2. How to Search Highly Cited Articles • Open “Google in English” • Search “Google Scholar” database • http://scholar.google.com/schhp?hl=en • Key in author’s name: CC Chiueh • Results 1 - 10 of about 7,560. (0.11 sec) • List of citations

3. A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1, 2, 3, 6- …[PDF] from pnas.org RS Burns, CC Chiueh, SP Markey… - Proceedings of the …, 1983 - National Acad Sciences Cited by 1875- Related articles - All 10 versions Hyperresponsivitiy of spontaneously hypertensive rat to indirect measurement of blood pressureCC Chiueh… - American Journal of Physiology- …, 1978 - Am Physiological Soc Cited by 260 - Related articles - All 3 versions Intracranial microdialysis of salicylic acid to detect hydroxyl radical generation through dopamine autooxidation in the caudate nucleus: effects of MPP+CC Chiueh, G Krishna, P Tulsi, T Obata… - Free Radical Biology …, 1992 – Elsevier Cited by 204 - Related articles - BL Direct - All 4 versions Neuroprotective properties of nitric oxide CC Chiueh - Annals of the New York Academy of Sciences, 1999 - Wiley Online Library Cited by 145 - Related articles - BL Direct - All 4 versions

4. Role of dopamine autoxidation, hydroxyl radical generation, and calcium overload in underlying mechanisms involved in MPTP-induced parkinsonism. CC Chiueh, H Miyake, MT Peng… - Advances in neurology, 1993 - Cited by 177 - Related articles - Cached - BL Direct - All 3 versions Centrally mediated release by cocaine of endogenous epinephrine and norepinephrine from the sympathoadrenal medullary system of unanesthetized rats.CC Chiueh, … - Journal of Pharmacology and Experimental …, 1978... Cited by 138 - Related articles - All 5 versions d-Amphetamine-induced release of" newly synthesized" and" stored" dopamine from the caudate nucleus in vivo.CC Chiueh… - Journal of Pharmacology and Experimental …, 1975 - ASPET Cited by 139 - Related articles - All 3 versions Biological stress response terminology: Integrating the concepts of adaptive response and preconditioning stress within a hormetic dose-response framework[PDF] from lrri.org…, N Cedergreen, MG Cherian, CC Chiueh… - Toxicology and applied …, 2007 – Elsevier Cited by 156 - Related articles - All 13 versions

5. 6-Fluorocatecholamines as false adrenergic neurotransmitters. CC Chiueh, Z Zukowska-Grojec, KL Kirk… - Journal of Pharmacology …, 1983 – ASPET Cited by 133 - Related articles - All 4 versions The roles of thioredoxin in protection against oxidative stress-induced apoptosis in SH-SY5Y cells[HTML] from jbc.org …, PB Chock, CC Chiueh - Journal of Biological Chemistry, 2002 – ASBMB Cited by 125 - Related articles - BL Direct - All 6 versions In Vivo Generation of Hydroxyl Radicals and MPTP‐Induced Dopaminergic Toxicity in the Basal Ganglia CHIUEH, CC, WU, R.-M., MOHANAKUMAR, KP, STERNBERGER, LM, KRISHNA, G., OBATA, T. and MURPHY, DL (1994), Annals of the New York Academy of ...Cited by 116 - Related articles - BL Direct - All 7 versions Apparent antioxidant effect of l-deprenyl on hydroxyl radical formation and nigral injury elicited by MPP< sup>+</sup> in vivo RM Wu, CC Chiueh, A Pert… - European journal of …, 1993 - Elsevier Cited by 132 - Related articles - All 5 versions

6. CC Chiueh: Research New Ideas • 1970s: • Release of brain dopamine by CNS stimulants (cocaine, d- and l-amphetamine) • Stress and hyper-adrenergic responsivity reflected by plasma NE, Epi, cortisol • 1980s: • MPTP-induced primate model of parkinsonism • Conversion of 6F-DOPA to 6F-catecholamines for PET brain imaging • 1990s: • In vivo trapping of OH radicals in the brain after dopamine overflow • Dopamine auto-oxidation in MPTP-induced nigral loss and parkinsonism • Antioxidative and neuroprotective properties of selegiline (l-deprenyl) for antidepression • 2000s: • NO as a neuroprotective agent • Effects of NO and Thioredoxin in preconditioning stress or hormesis

7. Long Citation Halflife • 2005 ~7,000 cites/ 113 pubmed articles • 2012 >9,700 cites/ 115 pubmed articles • Several classic papers with a long citation halflife >10 years; 24 articles cite for more than 100 times • Original research ideas • Frontier research projects • Quality >>> Quantity

8. Highly Cited Articles of TMUSearched by Winston W. ShenFebruary 28, 2012

9. Thirteen Most Cited Papers Published from TMU (Citation Numbers of Those More Than 100: Part 1 of 2) 430 Hsu YS, Chien RN, Yeh CT, Sheen IS, Chiou HY, Chu CM, Liaw YF. Long-term outcome after spontaneous HBeAg seroconversion in patients with chronic hepatitis B. Hapatology (Wiley online Library); 2002; 35: 1522-27 Chang Gung Memorial Hospital, Chang Gung University, School of Medicine, Taipei Medical University 336 Su KP, Huang SY, Chiu CC, Shen WW. Omega-3 fatty acids in major depressive disorder: a preliminary double-blind, placebo-controlled trial. Eur Neuropsychopharmacol. 2003 13 (4): 267-71. Departments of Psychiatry and Nutritional Sciences, TMU-Wan Fang Hospital 219 Chen YJ, Chen SA, Chen YC, Yeh HI, Chan P, Chang MC, Chang MS, Lin CI. Effects of rapid atrial pacing on the arrhythmogenic activity of single cardiomyocytes from pulmonary veins. Circulation; 2001; 104: 2849-54. Department of Cardiology, TMU-Wan Fang Medical Center and School of Medicine 270 Ho YS. Citation review of Lagergren kinetic rate equation on adsorption reactions. Scientometrics, Citation review of Lagergren kinetic rate equation on adsorption reactions. Scientometrics (an online publication, akademiai.com) 2004; 59: 171–177 School of Public Health, Taipei Medical University 174 Frank C. Gibson FC III, Hong C, Chou HH, Yumoto H, Chen J, Lien E, Wong J, Genco CA. Innate immune recognition of invasive bacteria accelerates atherosclerosis in apolipoprotein E-deficient mice. Circulation 2004; 109; 2801-6. College of Oral Medicine, Taipei Medical University 156 Calabrese EJ, Bachmann KA, Bailer AJ, Bolger PM, Borak J, Cai L, Cedergreen N, Cherian MG, Chiueh CC… Biological stress response terminology: integrating the concepts of adaptive response and preconditioning stress within a hormetic dose-response framework. Toxicol Appl Pharmacol; 2007: 222: 122-128. Institutes in Denmark, Canada, USA, College of Pharmacy, and Taipei Medical University 152 Ho YS, Chiu WT, Wang CC. Regression analysis for the sorption isotherms of basic dyes on sugarcane dust. Bioresour Technol 2005; 96: 1285-91. TMU-Wan-Fang Hospital, Taipei Medical University Based on the information of searching on “Taipei Medical University” in: WWW.Scholar .google.com as of February 28, 2012 by Winston W. Shen

10. Thirteen Most Cited Papers Published from TMU (Citation Numbers of Those More Than 100: Part 2 of 2) 137 Lee WR, Shen SC, Lin HY, Hou WC, Yang LL, Chen YC. Wogonin and fisetin induce apoptosis in human promyeloleukemic cells, accompanied by a decrease of reactive oxygen species, and activation of caspase 3 and Ca2++-dependent endonuclease. Biochem Pharmacol 2002; 63: 225-36. Inst. of Medical Sciences; Departments of Dermatalogy School of Medicine and TMU-Wan Fang Medical Center; Inst. of Pharmaconogsy Sciences; TMU 135 Chen YC, Shen SC, Lee WR, Hsu FL, Lin HY, Ko CH, Tseng SW. Emodin induces apoptosis in human promyeloleukemic HL-60 cells accompanied by activation of caspase 3 cascade but independent of reactive oxygen species production. Biochem Pharmacol 2002; 63: 1713-24. Graduate Inst. of Pharmacognosy Science; Departments of Dermatology School of Medicine and TMU-Wan Fang Medical Center; Institute of Medical Sciences, TMU 121 Ho YS, Wang YJ , Lin JK. Induction of p53 and p21/WAF1/CIP1 expression by nitric oxide and their association with apoptosis in human cancer cells. Mol Carcinog 1996; 16: 20-31. Sch. Medical Technology, Taipei Medical College 111 Hsu CS, Shen WW, Hsueh YM, Yeh SL. Soy isoflavone supplementation in postmenopausal Women: effects on plasma lipids, antioxidant enzyme activities and bone density. J Reprod Med 2001; 36: 221-6. Departments of Obstetrics and Gynecology and Psychiatry, TMU-Wan Fang Medical Center; and School of Public Health, TMU 110 Chen YC, Shen SC, Lee WR, Hou WC, Yang LL, Tony J.F. Lee TJF. Inhibition of nitric oxide synthase inhibitors and lipopolysaccharide induced inducible NOS and cyclooxygenase‐2 gene expressions by rutin, quercetin, and quercetin pentaacetate in RAW 264.7 macrophages. Journal of Cellular Biochemistry (Wiley Online Library)Graduate Institute of Pharmacognosy Science, Department of Dermatology School of Medicine, Department of Dermatology Taipei Medical University Hospital, TMU 101 Shen SC, Lee WR, Lin HY, Huang HC, Ko CH, Yang LL, Chen YC. In vitro and in vivo inhibitory activities of rutin, wogonin, and quercetin on lipopolysaccharide- induced nitric oxide and prostaglandin E2 production Eur J Pharmacol 2002; 446: 187-94. Departments of Dermatology School of Medicine and TMU-Wan-Fang Medical Center Based on the information of searching on “Taipei Medical University” in: WWW.Scholar .google.com as of February 28, 2012 by Winston W. Shen

11. Citations of JECM Articles 56 cites /124 articles =0.45 Journal impact Cites N Sum Journal Impact 6 2 12 200916/55=0.29 4 1 4 3 6 18 2010 40/69=0.58 2 8 16 <only 18% been cited 56/23=2.43> 1 6 6 0 101 0 (82%) <56 cites/ 126 articles>

12. Homework • A “do” and “don’t” list for responding to manuscript reviews www.ssc.wisc.edu/gender/Resources/R&RHints.pdfSimilar • Dos and Don’ts for Authors and Reviewers a special session of the AAI Publications Committee at IMMUNOLOGY 2009™ in Seattle, Washington May 10, 2009 the AAI Newsletter, November 2009–May 2010 www.aai.org/About/Publications/Additional/.../AAI_Dos_Donts.pdf • Study design (Reference website: http://www.jerrydallal.com/LHSP/STUDY.HTM)

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