SmartChem - Beyond Conventional Databases for Chemical Knowledge

1. Beyond Conventional Databases by ROW2 Technologies

2. Agenda • The ROW2 Background • SmartChem Overview • Live demonstration of SmartChem • 1

3. Our core strength Team of scientists with strong industrial chemistry experience Combined together forms SmartChem a knowledge base on Chemistry and Chemical Companies worldwide Commercial Team Developing a database of chemical suppliers worldwide

4. SmartChem-Underlying concept Pharma FP1 RMs Route 1 An Intermediate Agrochemical Route 2 FP2 RMs Route 3 Speciality FP3 Global Suppliers Global Suppliers RMs Business Development, R&D Sourcing, R&D • Business Development Professionals • Identifying Potential Customers for their Starting Materials(SM) and Intermediates (Int) worldwide. • Identify industry segments and products which consume their SMs & Intermediates. • World wide Competitors to their products. • Evaluation on new Products for Future development. • Sourcing and R&D Professionals • Identifying “Route Wise” RMs & INTs consumed in making APIs and Intermediates • Identifying worldwide sources for Finished Products (FP)/ Intermediates (Int) / RMs • Evaluating and identifying world wide sources for new / future Products (in the pipeline) identified by R&D and Marketing • Obtaining useful information to reduce excess inventory of RM’s and Intermediates

5. Beyond Conventional Databases • 4

6. Data coverage • Total number of compounds (Starting Materials (SMs), Intermediates, End products (EPs): Over 150,000 Chemicals, Sourced from 102 countries worldwide. • Latest molecules from Pharmaceutical, Agrochemicals, Fine & Specialty chemicals. • Phase II-III APIs as published in WHO List as “Potential candidates” and Drugs of Future • Raw materials and intermediates going into all the above molecules • Suppliers are categorized as Manufacturers, Traders, Catalog, Custom Synthesis, Custom Manufacturing, Contract Research companies, R&D Scale, Lab Reagent etc with certifications(ISO, WHO, EUDRA, GMP details of China, Japan, Brazil, Mexico, Canada and their regulatory details likeUSDMF/Japanese DMF/Korean DMF/Taiwan DMF/CEPs /GUDFA/EU Written Confirmation Holders / WHO etc • Company Specific Information on USFDA Warnings / EUDRA-GMPNC for Non-Compliance • Dosage Information / USFDA, ANDA-NDA & EMA Information for API’s and Veterinary molecules. • Patent term expiry data for Pharmaceutical molecules & Veterinary drugs were users can keep a watch on best selling drugs going off-patent thus exploring new business avenues and opportunities in the Pharmaceutical industry for US and Canada. • SmartChem has SPC data for Six countries (UK, Germany, France, Sweden, Slovak republic, Switzerland) from the European region. These dates are important for business development Professionals of Pharma companies as it gives a better picture about the global status of APIs and their exclusivity expiration details. • Impurity Profile - List of impurities from various pharmacopoeias (each impurity name has a suffix EP, USP, BP in its synonyms for its identification) • Registration information of agrochemicals from Europe, UK and India • Inventory information from countries like USA, Canada, New Zealand, Philippines • Company-wise listing of REACH registration data. • Reach Corner that provides key information on REACH Registered, Pre-registered, High concern substances

7. Addition & Validation of Companies Data Brochures collected from Events Trade Magazines Adding New Companies Online Directories Offline Directories Meeting companies in Events Phone calling • Validation of Companies Sending Emails Sending hard copy letters Referring Import Export Data

8. SmartChem Features • Impurity Profile- SmartChem has list of impurities from various pharmacopoeias (each impurity name hasa suffix EP, USP, BP in its synonyms for its identification) which appear as separate tab called “Impurity data” for APIs. • Reaction Scheme-Allows the users to view the sequential display of consumption of RMs and Intermediates in a chemical process of making APIs and complex Intermediates • Application Areas- Allows user to view various end-applications and/or commercial molecules that uses chemical of their interest as a raw material. • RapidFire Tool- A user friendly tool, which allows users to quickly select multiple target companies of their interest through various filters and send an email communication to them all at once • Aftersales assistance-Rapid and secured means to send ‘Updation Requests’ at just click of a button thus helping the users to save significant time and efforts.

9. Why SmartChem is Special A team of experienced scientists available to assist you Almost 93% of customers have resubscribed in the last 9 years With one click of the button quotes can be obtained From multiple suppliers SmartChem 16 Successful years of providing value to over 1000 users in 20 countries Our staff Takes pride in servicing customers needs Customers Feedback Dedicated experienced chemistry And commercial teams Allocation of resource for Continuous addition of New features

10. Testimonials "From the first day we owned it, SmartChem database became important tool in my daily practice – we found it very helpful for our portfolio management, products selection, alternative synthetic routes exploring , suppliers evaluation etc. Simplicity and faithfulness of the web based version makes the usage simple and very accessible. I wish ROW2 team to continue database development and expansion.“ -Alex Weisman PhD, CSOPerrigo API Ltd,  A subsidiary of Perrigo LLC. "I’ve been using SmartChem database for several years and I’m pleased to state that it’s a very important tool for the search of suppliers all over the world.The distinction among manufacturers, traders and catalogue producers is really useful for my job.Also the introduction of REACH status has been really appreciated."-Chiara VariniSenior Procurement Responsible Direct ProcurementLundbeck Pharmaceuticals Italy S.p.A. "This SmartChem we have used like our master source for data searches and has benefitted in different scenarios to us like we got end use information of our products so we developed new customers thus this enhances our sales revenue and in few cases we have got the information thru chemistry for selecting best route of our manufacturing processes.“ -Amit Mishra , Assistant Manager-Product ManagementJubilant Life Sciences Ltd.

11. Our Presence