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Understanding B Cell Classification in Cell Ontology

Explore the diverse subsets of B cells, including immature and mature classifications. Learn about the definition of B cells as lymphocytes expressing immunoglobulin complexes, and uncover details about plasma cells and B cell subtypes.

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Understanding B Cell Classification in Cell Ontology

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  1. B cells • 14 terms for B cell in Cell Ontology • Broadly divided into immature and mature subsets. • The genus term ‘B cell’ is the parent term for all types of B cell. • Plasma cell considered a distinct cell type.

  2. B cell definition • [Term] • id: CL:0000236 • name: B cell • def: "A type of lymphocyte whose defining characteristic is the expression of an immunoglobulin complex." [GOC:add, ISBN:0781735149] • exact_synonym: "B lymphocyte" [] • exact_synonym: "B-cell" [] • exact_synonym: "B-lymphocyte" [] • is_a: CL:0000542 ! lymphocyte • relationship: develops_from CL:0000826 ! pro-B cell

  3. B cells

  4. B cell Questions • early pro-B cell and late pro-B cells, and pre-pro B cells • Relationship of pre B cell and transitional stage B cell • Missing B cell subtypes

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