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SAN 2011. 5 th – 8 th May Thessaloniki CHRONIC FATIGUE SYNDROME SYMPOSIUM Chairs: Aisha Cortoos & Andreas Ioannides. Waking Brain Rhythms in CFS Implications For A Model of CNS Dysfunction. Lesley Parkinson Tomas Ros, Alan Parkinson, John Gruzelier,Rajendra Sharma. “New Model”.
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SAN 2011 • 5th – 8th May Thessaloniki • CHRONIC FATIGUE SYNDROME SYMPOSIUM Chairs: Aisha Cortoos & Andreas Ioannides
Waking Brain Rhythms in CFS Implications For A Model of CNS Dysfunction Lesley Parkinson Tomas Ros, Alan Parkinson, John Gruzelier,Rajendra Sharma.
“New Model” • Disrupted “faster” (>15Hz) brain rhythms in CFS during eyes open and an induced mental fatigue condition(VCPT)is suggestive of cortical hyper-arousal which may explain why cognitive dysfunction worsens with extended workload as the system “burns out”.
“New Model” cont: • There is likely to be a link between sleep dysfunction in CFS and EEG hyperactivity/cortical hyperarousal. • So we have a “cumulating sleep – debt “ model whereby reduced sleep efficiency which is CNS mediated leads to mental fatigue whilst also contributing to physical fatigue.