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Boc. -. -. D. -. -. fmk. Neurons MCF-7 Jurkat. Vehicle Q-VD-OPH Z-VAD-fmk. a b. Cells. LD 50 (µM). LD 50 (µM). Cells. Boc-D-fmk. Z-VAD-fmk. Q-VD-OPH. Z-VAD-fmk.
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Boc - - D - - fmk Neurons MCF-7 Jurkat Vehicle Q-VD-OPH Z-VAD-fmk a b Cells LD50 (µM) LD50 (µM) Cells Boc-D-fmk Z-VAD-fmk Q-VD-OPH Z-VAD-fmk Q-VD-OPH 24h 48h 48h 24h 48h 24h Neurons PC3 200 ± ± 5 5 250 ± ± 5 230 ± 10 380 ± ± 35 300 ± ± 25 410 ± ± 15 300 ± ± 20 500 ± ± 40 390 ± ± 25 Primary cells HT29 365 ± 15 367 ± ± 15 375 ± ± 25 PBMC 370 ± ± 40 260 ± 30 400 ± ± 25 260 ± ± 35 480 ± ± 15 310 ± ± 25 MCF-7 245 ± 10 230 ± 14 275 ± 15 HUVEC ND 280 ± ± 15 400 ± ± 15 300 ± ± 15 675 ± ± 25 ± ± 6 60 410 SF268 240 ± 30 380 ± ± 15 450 ± 20 Jurkat ± 430 ± ± 40 340 40 460 ± ± 35 350 ± ± 40 500 ± ± 40 340 ± 20 NCI H460 140 ± ± 10 140 ± 10 200 ± ± 15 Cell Lines HeLa Cells HD30 (µM) 425 ± ± 30 310 ± ± 20 430 ± ± 40 300 ± ± 15 880 ± 50 360 ± 40 MCF-7 RRC 350 ± ± 10 350 ± 10 500 ± ± 15 460 ± 290 ± ± 25 490 ± ± 25 320 ± ± 30 630 ± 60 ± 40 50 300 c d