60 likes | 251 Views
Neural processing of language in the absence of auditory input. Naja Ferjan Ramirez In collaboration with Matt Leonard, Christina Torres, Marla Hatrak , Eric Halgren , & Rachel Maybery Mayberry Lab Multimodal Imaging Lab Cognitive Neuroscience 2013 Spring Retreat &
E N D
Neural processing of language in the absence of auditory input Naja Ferjan Ramirez In collaboration with Matt Leonard, Christina Torres, Marla Hatrak, Eric Halgren, & Rachel Maybery Mayberry Lab Multimodal Imaging Lab Cognitive Neuroscience 2013 Spring Retreat & Kavli Institute for Brain and Mind Symposium
Early stages = modality specific AUDITORY WORDS WRITTEN WORDS • Are the neural underpinnings of word meaning dependent on auditory language experience? • Congenitally deaf individuals receive no auditory input • Some acquire sign language as their native language from birth Later stages = modality independent? Left dominant lexico-semantic network Marinkovic et al. 2003 Is the meaning of ASL signs in deaf native signers processed like the meaning of auditory & written words in hearing people (i.e. left dominant, fronto-temporal areas)?
Word Onset Anatomically constrained Magnetoencephalography Average waveform from single MEG sensor amplitude • Deaf native signers (n=11) watch ASL signs • Hearing English speakers (n=8) listen to English words ms 200 100 300 400 500 600 700
Integrating MEG (temporal resolution)… … with MRI (spatial resolution) ms 200 100 300 400 500 600 700 Method: Dale et al, 2000
Sensory processing: Modality specific Sign in native deaf 300-350 ms Speech in hearing 300-350 ms Lexico-semantic processing: Independent of modality through which early language is received Neural systems for high-level language processing are supramodal!
Thank you! NSF BCS-0924539 NIH RO1DC012797